Entrez gene ID | | 1635 |
Official gene symbol | | DCTD |
Full name | | dCMP deaminase |
Aliases | | ,MGC111062, |
Gene summary | | The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q35.1 |
Gene position | | 183838630 - 183811244 Map Viewer |
Gene orientation | | minus |
Gene size | | 27387 bp |
Gene sequence |
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OMIM ID | | 607638 |
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