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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACE (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1636 Official gene symbol ACE Full name angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Aliases ,ACE1,CD143,DCP,DCP1,MGC26566,MVCD3, Gene summary This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq] Location Chromosome: 17   Locus: 17q23.3 Gene position 61554434 - 61575741  Map Viewer Gene orientation plus Gene size 21308 bp Gene sequence >ACE:26828586..26849893:Length=21308 GCCGAGCACCGCGCACCGCGTCATGGGGGCCGCCTCGGGCCGCCGGGGGCCGGGGCTGCT GCTGCCGCTGCCGCTGCTGTTGCTGCTGCCGCCGCAGCCCGCCCTGGCGTTGGACCCCGG GCTGCAGCCCGGCAACTTTTCTGCTGACGAGGCCGGGGCGCAGCTCTTCGCGCAGAGCTA CAACTCCAGCGCCGAACAGGTGCTGTTCCAGAGCGTGGCCGCCAGCTGGGCGCACGACAC CAACATCACCGCGGAGAATGCAAGGCGCCAGGTGGGCGCCCGGGCCCGGGCGGGGGCGGG GCGGGGCCGCGGCGGCCAATCACAGCACGCGGCCGGCTTGTGGGGCGGGCAGGCTGGCGC CCCCGACCCGAACCCCACCCCGACCCCGGACCCTCGCCCCGACAGTCAGCCGCGGGGCCC GAGCGCCGGGCTGCGCGCACGGCCTGCGCTCCCAGCATGCACGAGTTGGATGGATGAGGG TGGCTGCTCCCAGGCCGCGCCCGCCTTCGCCGAAGGTGCTGGGCTTGGCTCTGGGGCCCC CGCGCTCTCGGGCAGCTGCCTTCTCACCTCCGGACGCTGTCGCTGTCACCGTCACCGCAC TGCACTGTCCATCCACCCTCCACTCGCCCGGCCTCTTTTCTGGTCCCAATTTCTGCTCCA CCATTCCCATGAGGCAGATTCCCTCCAGAAGGAGGAAGCGCGGCTTCCGCAAACTAAGGT CTCCCGCAGGGATCTCCCCAGGGCCCGGGCTCTGGAAGCCCTTGGCCTTCCTCCCCTCCC CCAGCACCGTGGCTTCTCCTTTATGGCCTGCATCTAAGCAGGGTCCTACACCCTCCCTGC CCTCCTGGTGCCCAATAGGAGGAAGCAGCCCTGCTCAGCCAGGAGTTTGCGGAGGCCTGG GGCCAGAAGGCCAAGGAGCTGTATGAACCGATCTGGCAGAACTTCACGGACCCGCAGCTG CGCAGGATCATCGGAGCTGTGCGCACCCTGGGCTCTGCCAACCTGCCCCTGGCTAAGCGG CAGCAGGTGGGCTGAGGGCTGAGGCAGAGCTCGGGGGCGGCCTCCTAGTGCCCCATCGTG GGGGTCGGGGGAGAGCAGCCCATCAGGGAGGGAGGAACCCTGGGATCCACATGGGCCCTG ACAGAAGGGAAAGCCCAGGTAAGCACAGAATGGCTTTCTGAGCATTGATTTTTCTTGGAG ATGGGGTGGGGAGTTACTTTCTGTTAAAGGAAGCATTCTGGAGTAGGAAGCCAAATTCAA ATACACTTCTCCCTAGGCTGGTTTATGAGCTTCTTTGGAAGAGTTGAGAAGGGCTGGGCG TGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGCATCGCTTGAG CCCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCTCGTCTCTACAAAAAAAAAA TAGCTGGGCTTGGTGGTGCGTGCACCTACAGTCCCAGCTACTCTTGAAACTGAGGGGGAA GGATCACCTGAGCCCAGGAGGTCAAGGCTACAGTGAGCTGTGATTGCACTACTGCACCCC AGCCTGCGTGACAGAGTGAGACCTCCCCCCAAAAAAAAGAGAGAGAGAAAAGGTTGAGAA AGACTGGGAAGTCACCAAAGCCAGAGAATGGGAGGGATCTGCCCTCACTGCAGGGTGGTG CCAAGCTGGGACTTGACCCTGACCCTGACTTTCAGGACTCCTGTCCCCCACTCCACAGGC TGCCTCCACTGGCAGGGGACTCAGAAGTGATCCGGTCACACTAAGTGACACTTAGTGATC AGAAGTGCCCCGGTGCCACTGAGTGGCCTTGTCCAAGCTACATCCACTCTGTGGGCTCCT CCTTCTAGCAGCGAGGGGAGGGCAGATGTCCCAGGGGCTGGTCACTGGAGCATTCCTCCC CTCTGACTCCCCAGTACAACGCCCTGCTAAGCAACATGAGCAGGATCTACTCCACCGCCA AGGTCTGCCTCCCCAACAAGACTGCCACCTGCTGGTCCCTGGACCCAGGTACGGCCCTTG CAGCTCCCCTCTCGGCGGTGCCCTAGTGTTCCCACATTGCCCTGCTGCACTCCAGACCAT GCAGTTGTGTAGGGTCTGTGGAGACAGCAGGTAAACCCAAAGGTGTTGCCCTCCAACTGG GGCTGGACGGTGCAGATACCCCCACGCCCTGCTTCTCTTGGCAAGTGGACTTCCGGAATC TCCAGCTGCAGCCCCCACTTCTGTGTGTACCTCGGCCTCTCCCATCACCCCTAGGCCTTC CTCCTGGCTGCCTGGTTTCCCCTTTCGTGGGTCCTCTCATGTTCCCCAAGAGCCCTCAGG CCAGGGACCCCTCGTGGCTTCCCCTTAAACCCCGCTCCAGCCCCCTTTATGAGCAGCTTC GAGGAAGGCACTCCATCCAATAGGCCGCTAAGTGTCTGTCTGGGTTTTGGCCTTTGGGTG TCCCCTTGGTGTCAGCCACCTTAGGTGGTCATGTCTCTGGGGCAGGGGCCCTGCCTGGGT GTTTCTGTAGCTCCCAGCCCCCTCCCACCAGGCCTGTAGGTGGCCCCTGTCTCTGGGGGC ACCGTGATGTTCAGGAAGCTGGTGGGAGCAGTAAGGACTGGTGCAGGCTCTGGTGAAGGC CGTTGAAGACTTCAACGTGGAGGCCTCCTCACCGACCCTGCCTGCCTGTGTCTCAGATCT CACCAACATCCTGGCTTCCTCGCGAAGCTACGCCATGCTCCTGTTTGCCTGGGAGGGCTG GCACAACGCTGCGGGCATCCCGCTGAAACCGCTGTACGAGGATTTCACTGCCCTCAGCAA TGAAGCCTACAAGCAGGACGGTGAGCAGGCCTCTCCCTGTCCAGGAACCACGCCAGGTGT CCTCTCTCAGCTGTCTCCCCAGAGTCCCAGCCCAGAGTCAGGCAGAGCAGCTGGTATGAC AATTCCAGCAGGCCCTGAGTTTCCCAGAAAGTGGAGGTGGGACCGGCCTGCACCCAGTGT GCCTGGACTTTGCTGCTGGCCTGCCCCACGTGGCCATCCTGCTGTCACTCCTGGCCCTGA TGCTCCTCTTTGCCTCTGGGAACCTCCAGGATCTGTTTAGCTGGCTGTAGCTAATTAGAA ATTGTAGAGTGGCAACCCCCAAGCCAATTTTCCAGCTAGCTGCAGATCCACGGGCCTCGA GCCAGTGGAAGAGCCGACTTACAGCTGAGAGGCTGAGGTCCGAGCCTTTGGCCTGAGCTA CATACCTCACCCCCACGCCCCCAGGCTTCACAGACACGGGGGCCTACTGGCGCTCCTGGT ACAACTCCCCCACCTTCGAGGACGATCTGGAACACCTCTACCAACAGCTAGAGCCCCTCT ACCTGAACCTCCATGCCTTCGTCCGCCGCGCACTGCATCGCCGATACGGAGACAGATACA TCAACCTCAGGGGACCCATCCCTGCTCATCTGCTGGGTAAGGACCTGGCCTCGCCTCCAC ATGAGTCCCACGGAAGTGTGGGTCCCGAGGTAGGGGTGGGGGATGTCCAGGGTAAGGGAA GGTGGGTTGTGACCCTCACATCTCACATGTGTGGGGCATCATACTGTTTGCTTCACATGC AGGAGACCATTCGTGTTCCCACTTTACAGGTGGGGACCCTGAGGCTTAGGGTCGTGAGGG ACTTAGTGGTCAGAGAGCTAGGGGCCAAACCAAAGGCTCTGGCCCTGGGTCCAGTGGGGG AGCCATCAGCCTAGCTCATGCCCAAGGAAACAAGCACTGTGGCCCTGCCTCAGGATTGAG TGGCTGGGGCCTGGCACAGCCAGAAATGACAGTGGCAGCATCTTGCAGCCCCAGGACATG TGGCCCTCGGAGGAGTGTGGGTGGGACTGATGTGTGAGATTTCTGGCCCTAAGCCAGGCC TGCAGCCCTTGAGGGCCCCAGGGTACAGGTGCCGGCCCCAGGGTGCCACTCAGCGATGCA TGAAGAAGCAGGCACAGCCAGGCAGGGAGCCAAGCTGTCCCCTTCCTTCCTTATCTAGGA GACATGTGGGCCCAGAGCTGGGAAAACATCTACGACATGGTGGTGCCTTTCCCAGACAAG CCCAACCTCGATGTCACCAGTACTATGCTGCAGCAGGTAAGCTCTGGGCTCAAGCCTGGG GTGGTGGGGGTCGGGGGTGGGGCGCAAAAAAAGGGAGTCACAGATGGGCACAGGGGCGGG AAGGTTTCGGGTACTGAGCAGCAGCCTGGTGTGTCTGTAGGAGCAGTGAGCTGGGGTCGG CCCCCTCAGTGAGGTGCCAGCTCCTCCCTCCAGGCTCCACAGTGGCAGGATGAGAGCAAC AACGCACTTTCACTCATCTGCTGTGGGAGTGAGGGCCCTGCCTCTGGGAATGGTGGCCAC AGAGCAGAGAAGCTTTCATGCACAGGGAGTTGACCCGAGATGGGGACCCCAGCCCTGTCC CCAGGCCAGCCAGAGTGGGCTCCCCCTGACCTGGCTCCACACCCCTCCTCCAGGGCTGGA ACGCCACGCACATGTTCCGGGTGGCAGAGGAGTTCTTCACCTCCCTGGAGCTCTCCCCCA TGCCTCCCGAGTTCTGGGAAGGGTCGATGCTGGAGAAGCCGGCCGACGGGCGGGAAGTGG TGTGCCACGCCTCGGCTTGGGACTTCTACAACAGGAAAGACTTCAGGTTCAGACATGGGA AGAGCACGTTCTGGGGTTCCCCGGTTCTGGGGCCCGGGGAAAGGCAGGCAGCCCAGGCGC AGGGAAGCTGGTTCCCAGGCCTGCCTCTACCCTACCCCAGCACTGGTTGGAGGCTGGGTC TGTTCCAGGGCTAGGGGGTATAGGAGGCCTATTAGTCCACCTTCTCTGGCAGCTTTGACA AATAGTCACTTCTATACCTTGGAATGGAGGAAGAAGGCCCAAGTGGTGGTGAGCCAGGGC AGGGTAAAGAATTTGCTTGTTTCTGCCAGGCACGGTGGTCACACCTGTAATCCCAGCACT TTGGGAGGTCAAGGCGGGTGGATCACCTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAAC ATGGCGAAACCCCGTCTCTACTAAAAATACAAAAATAAATTAGCCAGGGGTGATGGCGGG CGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAGGC GGAGGTTGCAGTGAGCTGAGATTGTGCCACTACAGGCCAGCCTGTGCAAAAGAGTGAGAC GCTGTCTCAAAAAAAAAAAAGAAAAAAAGAAGTTACTTGTTTCTACTGCGGCTTCATGCC CCAGGGCAGCTCCCTCCTCATTCCTGTCTTTCAGGTGCCAATCTGCCCTGTGCCCTGGCC CTGCCCTGTTCTGTCCATCCGTCACTCTCACCCTCGCCCTCTCTACGCCCCAGGATCAAG CAGTGCACACGGGTCACGATGGACCAGCTCTCCACAGTGCACCATGAGATGGGCCATATA CAGTACTACCTGCAGTACAAGGATCTGCCCGTCTCCCTGCGTCGGGGGGCCAACCCCGGC TTCCATGAGGCCATTGGGGACGTGCTGGCGCTCTCGGTCTCCACTCCTGAACATCTGCAC AAAATCGGCCTGCTGGACCGTGTCACCAATGACACGGGTATGGGAGGGCTGAGAGGCCCC CACCCAGCCTCACCTAAACCCCGCTCCACCCCACAGCAGGACCTCACTTGCCCCACTCAG CTCTGCCCTTCTTTCTGCCTCCCGGCCCCAGGTCAGGCAGGGTTCGGGATCCTCCTAGAG CCTCACGGTGCACACTGCGCCCAGCTCAGCACACCTGGGGGTCCTCTTCCAAGCAGGGCC CAGGGTCTCGAGGGCCAGCCATACCTTCTCTGCATCTCCCTGGCCTCACTTTCTGCTGCC CCGCCAGCCCACACTCTTAGGGGACCCTCTTCTCCCTCTGACCTCTTCCCTCTCCTTTCA TCTCATCTCCCAACAGAAAGTGACATCAATTACTTGCTAAAAATGGCACTGGAAAAAATT GCCTTCCTGCCCTTTGGCTACTTGGTGGACCAGTGGCGCTGGGGGGTCTTTAGTGGGCGT ACCCCCCCTTCCCGCTACAACTTCGACTGGTGGTATCTTCGGTGAGAGGAGGGATAGAAA AGCCTTCGCCCCAGCTAGCCCTCCCCAGCCTCCTGGACAGCCAGGCGCCTCCTGCCCCAG CCAGTTCTAGCCTCTCCTCTCTAATGATGTCCCCCGCTGTGACCCACCGCCTTCTCCTTT CCTGCCTGAAACTCCCTCTTCCAGGAAGTCTTCCCCAGTTCCTCAGGATGGGGAAGGGTT GCCGGGTGGAAATGCCTTTTCTACAAAAGTTAAATCCATCTGTTTGCAACCTCTAGGCCC TAAGACAATTTAACCATCCTTTTCCAGAACCAAGTATCAGGGGATCTGTCCTCCTGTTAC CCGAAACGAAACCCACTTTGATGCTGGAGCTAAGTTTCATGTTCCAAATGTGACACCATA CATCAGGTATTAGCGCCCCCACCCCACCCACCCCCAGTACTGTCACACCCTCAATCCACT TCTCCTCCTGTGATCCTAGCTGCCTCATCCCCAGGGCTTGTCCCCATGCTCCTCCAGACC TCAAAGGCCTGGAGTTAGAGTGGCCCACTCTCCTGAGCCTGTCTTGGGTCTCCCTTCTCC CCCAAGATAGCTTCTGGTCCAGCCTCTGCCCTGCAGGAAGCTGGATGGTGCCTGGGTAAG GAACCCCTGTTCCTGGCCCCCCATGATCTTCCCTGACTCCCACCCTGTGCCTGCAGGTAC TTTGTGAGTTTTGTCCTGCAGTTCCAGTTCCATGAAGCCCTGTGCAAGGAGGCAGGCTAT GAGGGCCCACTGCACCAGTGTGACATCTACCGGTCCACCAAGGCAGGGGCCAAGCTCCGG TGTGTGGTGGGAAGCCGGGGGAAGTGGGAGGCAGAGAGGAGCGGCTGGCAAAGGGTGTGG CAGGAGGTGTCTGGCTGCTCTGATGGGGTGGGGGGCACCAACCACAGAGCTGGACTGATG TGGATGCCTGTCTCCTCGCTATGTCATCAAATATTTATTGAGTGGGCCTTCTGGCTGGCA TGGGGCGACACAAATGCCCCCTGCCACCATCAGAGAGATCCCAGGCCCCAGGGTCTTATT GCCACAGTTTCTGCAGTCCATTGGGGGGCGGAAGTGGCCAGGGGCATGTGGGCCGGGGTC CAGGAGCAGACTCCAGCCTGAGTCCCCTGTGCCCATGGTACCCACTCTGCCCACCAGGAA GGTGCTGCAGGCTGGCTCCTCCAGGCCCTGGCAGGAGGTGCTGAAGGACATGGTCGGCTT AGATGCCCTGGATGCCCAGCCGCTGCTCAAGTACTTCCAGCCAGTCACCCAGTGGCTGCA GGAGCAGAACCAGCAGAACGGCGAGGTCCTGGGCTGGCCCGAGTACCAGTGGCACCCGCC GTTGCCTGACAACTACCCGGAGGGCATAGGTAAAGCCCTGAGTGAGGATGGTGTGGGGCT AAGGTGGGTCCTCAACTCTGGGCTTGGCCCAGGCCCCAGGTTCCTGGTCAGCTCCTACCA GCTGAGCCCTGGTACCCTGTCCTGGAGGGCCAGGCAGCCCCCCAAGCTCATCAGCAGGGC CTGCGAGTGGGGACAGGCATGTCTTTCCCCCAGCATCCTAGAGAGGGTGTGCTCAGACCT GAGGGCCCCTCCCCTTCCAGAGGAAGCCAGACACAAGGCTCTGTGAGGTCACACTGCGGG CTCCGCTCTTATTGGCCAGGGGACGGTAGCTGCAGGACTCTGCTCTCCTGCGGCCATGGG CCAGGGTTGGGCTACTGCAGGACTTCCCAGCCTCCTCTTCCTGCTGCTCTGCTACGGGCA CCCTCTGCTGGTCCCCAGCCAGGAGGCATCCCAACAGGTGACAGTCACCCATGGGACAAG CAGCCAGGCAACAACCAGCAGCCAGACAACCACCCACCAGGCGACGGCCCACCAGACATC AGCCCAGAGCCCAAGTGGGACCATGCAGGGGAGGGGCAGGGTGCCAGGGGTGGGAGAGGC GGGGCCGGGTAGGGACAGGGCAGGGTACAAGGGAGTGCGAGAGGGATAATGGCTTCTGGT GAGACCACAAACCTGGAGAGGGGAGGCAGAGGTTTGTCTGTTTCCCTGCACTCTGTCCCA CAGACCTGGTGACTGATGAGGCTGAGGCCAGCAAGTTTGTGGAGGAATATGACCGGACAT CCCAGGTGGTGTGGAACGAGTATGCCGAGGCCAACTGGAACTACAACACCAACATCACCA CAGAGACCAGCAAGATTCTGGTGGGAGCCACCTCCCCACCCCCAAACCTGAGCATGTGCA TACACACAGAGATGCTGTCCCGCTCACCACACAGTGGGGCTGCCACCACATTTTAAATTG AATATTTAAAACAATACTCAATTTCGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAG CACTTTGGGAGGGGGAGGCGGGCGGATCACGAGGTCAGATCAAGACCATCCTGGCTAACA CGGTGAAACCCCATCTCTAGTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGAGCACCT GTAGTCCCAGTACTCAGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCAGAGCT TGCAGTGAGCCGAGATGGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATC AAAAAAAAAAAAAAAAAAAACTCAATTTCAGATTTTGATGAACATTTACTCAATGCCTGA GCAATTCTTCTTTCCTTAAAAATCAGTCTCTGGGAGGCCTAGGTGGGAGGATCACTTGAA GCCAGGAGTTGGAGACTAGCCTGGGCAACATAGCAAGATCCCATCTCTATTCAAACAAAC AAATAAACAAAAATCAATCTCTAGTAACAGAATAATTTGTACATAAATAAGTGGTGCTCA AGTCGTTTTTTAAAAGATTGAAAGCCTCTGTTTGTCTCCTCTACAAAAGGGGCTACACTT CCTCTTTACCCTCATTCCCTGCCTATTTGGCTGAGCACAAATTATGCCACTGAGCCACAC ACTGTTACTGTTCCTTGGCACTTTGATCTGTTGCCTCATCTTTTTCTCAACAGCCTTGCA AAATTGGTGAGCTTATTCCCATTTTACAGATGGGATTTGATATTAACTCTGAGGTTCAGA AAGGCCACAGAGCTAATACCAAGCTGGCTCCTTCCTAAGGGCCTTTACGACACTTGGGGG TCTTCTCTTCTCTGCCCCTGCCTGGATATGTGTTGCTTGACCGCAGGCATCCAGGGAGGG TGAGTACTGCATCCAGGACGTTATCAGCGTCCAGCTTGCAGAGAGTCTTATAGGCAAAGG TTGCAACTTAATTCCACTGCCCCCTCACCACCACCTCCAGCCCTCAGCTCCCACTTGGGG CCTCCCGCTCAGAGGCTGCTCTGGAGCTCCTGGGCCCTGTGACACCATCCCCCTGTGCCC TCAGCTGCAGAAGAACATGCAAATAGCCAACCACACCCTGAAGTACGGCACCCAGGCCAG GAAGTTTGATGTGAACCAGTTGCAGAACACCACTATCAAGCGGATCATAAAGAAGGTTCA GGACCTAGAACGGGCAGCACTGCCTGCCCAGGAGCTGGAGGAGGTGTGTGGCTCGCAAGG TACAGGGAGAGGGGAATCCTGGGGCAGTGAGCCCAACACAGGGTCTGGCCTGGCCTTCAC GCTGCTTCCTCTTCCTCGTTGTATCAAGTCATGGCATCTGCCATGCGATGTGCACCTCAG AACTGCTGAGAGGGCAGCGCTCCCCAGCTCCCTGGCTCCCCACCTGCCAGCCCATGGGGC CTGGGGGTAGTGCAGGCCCCAGAGAGACCAAGTGCAAAGGAGTACAGCTCATTGCCTCTC CTTCCTCCTGCAGTACAACAAGATCCTGTTGGATATGGAAACCACCTACAGCGTGGCCAC TGTGTGCCACCCGAATGGCAGCTGCCTGCAGCTCGAGCCAGGTGAGAGCTCATGTGCAGG CTGAGTGAGAGGCGAGGGCTGGGACTGGCATGGGGCCCGGGGGTGCTGGGTGAGAGCACA GAGTTGGGTTCCCCTCGCTCTTGGGGTCAGCGTGCCCAGGAAATGCCCTTTCTTGTTTTC CACGAGGGGGGCTTCTCTGCCCCACTGAGAGCCGGCACCTACTTCATACCATGCCCCGAT CAGCTGCCCCTCCCTCAGAACCGCCCTCTGCTTAAGGGTGTCCACTCTCTCCTGTCCTCT CTGCATGCCGCCCCTCAGAGCAGCGGGATCTCAAAGTTATATTTCATGGGCTTGGACTCC AAATGGGGGGAACTCGGGGACACTAGCTCCCCCCGGCCTCCTTTCGTGACCCTGCCCTTG ACTTCCTCACCTTCTCTGTCTTTCCTGAGCCCCTCTCCCAGCATGTGACTGATAAGGAAA TTGAGTCACACAGCCCCTGAAAGCGCCAGACTAGAACCTGAGCCTCTGATTCCTCTCACT TCCCTCACCTACCCTGCCACTTCCTACTGGATAGAAGTAGACAGCTCTTGACTGTCCTCT TTTCTCCCCACTGGCTGGTCCTTCTTACCCCGGCCCGTTTGAAAGAGCTCACCCCCGACA CAAGGACCCGCACACAGATACCTCCCAGCTCCCTCTCAACCCACCCTTTCCAGGGTTGGA GAACTTGAGGCATAAACTTGCTTCCATGAGGAATCTCCACCCAGAAATGGGTCTTTCTGG CCCCCAGCCCAGCTCCCACATTAGAACAATGACAAATAGAAGGGGAAATGGAAAATAAAC AGGAGAAACGGTTTTCCCAGGACAGGGTTTGGCCTACAAGTTGTGGATGTGGGTACCCAT GCCAAGTGTGAGGGGAGGCTGGCCGGGTGTGGTGGCTCATGCCTCTAATCCCAGCACTTT GGGAGGCCAAGGTGAGTAGATCACTTGAGGCCGGGAGTTTGAGACCAGCCTGGCCAACAT GGTGAAACCCCATCTGTACTAAAAATACAAAAGTTAGCTGGGCGTGGTGGTAGATGCCTG TAGTCCCAGCTACTTGGGAGGCTGAGGCATGAGAATCGCTTGAGCCCAGCCTGGGCAATA CAGCAAGACCCCGTCTCTACAAATAAAATACAAAAAATTAGTTGGATGTGGTGGTGCATG CCTGTAGTCCTAGCTGCTAGGGAGGCTGAGATGGAAGGATTGCTTGAGCCTGGGAGGTCA AGGCTGCAGTGAGCCGAGATGGCGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCC TGTCTCAGAAAAAAAAAAAAAAAAAAAAAGGAGAGGAGAGAGACTCAAGCACGCCCCTCA CAGGACTGCTGAGGCCCTGCAGGTGTCTGCAGCATGTGGCCCCAGGCCGGGGACTCTGTA AGCCACTGCTGGAGAGCCACTCCCATCCTTTCTCCCATTTCTCTAGACCTGCTGCCTATA CAGTCACTTTTATGTGGTTTCGCCAATTTTATTCCAGCTCTGAAATTCTCTGAGCTCCCC TTACAAGCAGAGGTGAGCTAAGGGCTGGAGCTCAAGGCATTCAAACCCCTACCAGATCTG ACGAATGTGATGGCCACGTCCCGGAAATATGAAGACCTGTTATGGGCATGGGAGGGCTGG CGAGACAAGGCGGGGAGAGCCATCCTCCAGTTTTACCCGAAATACGTGGAACTCATCAAC CAGGCTGCCCGGCTCAATGGTGAGTCCCTGCTGCCAACATCACTGGCACTTGGGTCCCTT CATTTTCCTCAAAGAGGTGCTGTGAAACCCCAAGCCTAGGAAAAGGTAGATCCCTGGAGG AGGCAGGTAATGTGGTGTTGGGAGAGCCTGGCTGTGTCCCCTCTGTAGGCTATGTAGATG CAGGGGACTCGTGGAGGTCTATGTACGAGACACCATCCCTGGAGCAAGACCTGGAGCGGC TCTTCCAGGAGCTGCAGCCACTCTACCTCAACCTGCATGCCTACGTGCGCCGGGCCCTGC ACCGTCACTACGGGGCCCAGCACATCAACCTGGAGGGGCCCATTCCTGCTCACCTGCTGG GTAAGGGCACATGTCGGGCCTTGAGGAGGGTAAAGACGGACCACAGTGTGAGTGAGGGTT GGGACAGGGCTGACTAGAGGGTAGGGAGCAGGCTGGGGACTGAGAGACTCCAGCCCTGTG GGGGATGGTTGCCCAGGCTGGAGGGGGGTGGGCGCTGGGAGTGGGGAGCCCCCCACTTGC ATCTGGTGCCACATTCACTGCAGATCTATGTCGGGCAAGTCACCATGGATGGGGGAAGAA GTTAATAATCTTGTCCAGGAGACCACGGCACCCATCACAACATTGTGTGATCTTAGAGGG CGAGGAAGAGGCTGTGAGTGGGAGCTGGGGAGGCTTTGCCAAGAGGTGGCCTGTGAGCAG GGCCTCGGAAGATGACAGGGTTTGACAGATGGGAAGTGGGGGATGAGAGGACAGACGCAG TGTTCAGGCCAAGGGAACTGGAACAAAGAAGAACCTGAGAATGTAAATCTACTTCAACCC TGGACCCTCCTTTGCCAAGGGCTGCAATCTCAGATGCCCTGAATGTGTGAAGTAGGCGGT GAGGACAGTAAGGGATGGTAGGGAGTAAGGCAAAGCAGAGGCTACTGGTTCTCTGTCCCT GATGGGCTGTTAGGAACACTTTCCTGGAGCAGAGAGACCAGACAGGCCCTCAGACCATTT AGAAACTATAAGGGAGGCCCCAGAGGACGGCCTGGCTGTGGGTCTAGCTCCCACACAGGC TGGGAGTCCAGCCCTCTTCAGCCCCTCTCTGGTGAGACCAAAGAACATCTGGTGATGTCA CAGTGGACGTCAGTTCACCAACTGGGAGACACAGGCCCCGGGAAGAAAAGCAACATGCCC AGCGTGGCCTGGGAGCTGGGGCAGAGCTGGCCTTAGAACTCAGCCCCTGACAATTGGTAA AAGGGGAAAGGGGAGCAACCTAACACTGATGCGCTCTCTGTCTCTCTCTCTGGCTCTCTC CCTGGCTCTCTCCCTCTTCTCTCTCATGTTCTCTCCATCACTCATCGCTCTAACCCTCTC TCACTGGTTTGCACTTTAGACTTCATCTGATGTCAGCCGAAGCTTCACCTCACTTGGCTA GGAAAGAGCCTTGAGTCCAAATCTGTTTCTGAGCCTTCCATTCATCCTGAGTTTCTTCCT TTTCCTCTGTCGTGGAGAACTAGGCTCTTTTCTTACACTAAACTCAGAGGCATCAGCCTC TCCTGAAGGAGACGGCTGGTTCCTGTCAGAGTTGCTGAGCTGCAGACACCGACCTCAGGT GGTGCGGAGGGGACATGGCAGAGTGGCTGGTGAAGAGAGCAGCCTGCCAGCCTTTCAATC CCAGCCCTGCCACTTAGGAGCCGTGGGCCCCCGGCGAGGGGGGCGGTCACTTAACTCTCC AGCCTGTTTCCTTTACTAGCCAATGGGAATCGTGACAGTACCTGGGTGCAGACAGGATTG AAAGTGAATTCACACAATGTTCTTGGTGCAGAGCCAATAAGAGGTGGCCACCGGGGTGTA GGTGTTCTGGGGACCTGTAATGTCCTCACATGTCAGCAGTTGCTAGTCACATTGGTCTCC ACTGCTCACGGACAGTGAAGACCACCTGGATTCCCTGATAACCAGCAAGGCCCCCACCTA GAGCCAGGCAGTAATGACCTACTGGGCTGGATATGCACACCAAAGATGATGTGTGCCTCA AAGCTTGCAAACAGTAGGTGCTCAAGAAATGCCACTATGATTAGCAGGACTGGGATCTGG AGCGCTCTTCCTGCAGGAGGGCATTGAGCCTAAGTAACATTTGTCTTTCCTCTCTCTGCC GTCCCCCACACTCGCCTCCAGGGAACATGTGGGCGCAGACCTGGTCCAACATCTATGACT TGGTGGTGCCCTTCCCTTCAGCCCCCTCGATGGACACCACAGAGGCTATGCTAAAGCAGG TCCGCACCAGCCCAGGGGCAGGGAGGCCCCGCCGGGATGGGAGGGACCCTCTGATTCAGG AGTTCCCTCCAGTTTAGCCCTCCCCCGGGATCCCCACGGCAGCACGCAGTCTGTCCCCGG AACCCCCAGTTTGGGCAGAACTCCCTCTGCTTGCAGGGCTGGACGCCCAGGAGGATGTTT AAGGAGGCTGATGATTTCTTCACCTCCCTGGGGCTGCTGCCCGTGCCTCCTGAGTTCTGG AACAAGTCGATGCTGGAGAAGCCAACCGACGGGCGGGAGGTGGTCTGCCACGCCTCGGCC TGGGACTTCTACAACGGCAAGGACTTCCGGTACATCCAGCTAGGGCTCAGGTCTCGTTCC TGAGCCCCACGGGCAAGGGAAATGAACCAAGCAAAGGGTCCACTACTGTCCCCCAGCTGG AGCCAGCAGGGCAGGATGGGGACAGGGCCAGAGTTTGGGACTGAGTGTCTAGAGAGGTGT TGGCTTCTGGCAGGAAAACCCCATCCGCCTGATGGGGACTTCTGAAGCACGCAACAGCTC TGTCAGCCTGGCCGCTGGGAAGTGCTCAAGGTCCCAGTCCTGGGTTTGAGCATGGTAGGC TGCCCCGCGTCCCTCCTTGGGAGCAGCCCCTGCATGGAGCTGGCCTCTCCCTGGGGGCAC ATGCTGTGACACAGGGAGGCACACGAGGATGTTGGGTGCTCTGTACAGATCCACTCTCAC CCCTGACAGGCTCAGAAGCTGCCTTCCTTGGAGGATGGCGTTTTAGTTACCTATTGCTGT GCAACCAAGCACCCCAGAGCTTAGCCTTACGAAACAACCAGTTGATTTTGCTTATGATTT TATGTGCCAGGAATTCAGGCAGTACACAGTGGAAATGGCCTTTCTCTACAGGGCCCCCTC TGTTGGGGGCAGCTCTCACAGCCGGGATGGCTCAATGGGGGCCATACGTCCAGAGCCCCA GTTCTGGCTGTCGGTTGAGGTCCTCGGTTTTTCCCATGTGGCAGATGCTGGGGCACATGT TCCCAGTGGCCTCTTGGCTCACATGTTGGGTGCTTGGGGTGAGATGGCTGGAACGGCTGG AGGTGGGTCAGGCATCTCTCCAGGCTAGCTCGGGCGCCCTCCCAGCGTGGAATCTGAGGT GGGCAGATTTACCTGGCAGCCAGCATCCCCCACAGCAACTACTGACGCAGCCAGTTCTCA AGGCTAGGTCCAAAACTGGCCCAGAGTCACTTCTGCCATGTTTTATTGGCTAGAACAAGT CACAAGTTCACCCAGATTCAAGAGAAGAGAAAAAAGTCCCTCCCACTTGGGAGAAGTGGC AAAGACCATCTGTCACAGCTGAAGAAGTGTCTCTTACAAGGAGAACAGACACGGGGAGCC TGAAACAAAACCCGATGGGATTCCCTGGGCTGTGCAGGCCCTTCCAGGCATGAGGACTCA GCCACAGGGCTGAGAGGAGACAGGATCTGGGGGATGAGAGCCCTTGTGGGGTCTTCCCTT TTATGGGGAGTCAGAGGAGAAGCTGGATAGATCCCCAGCCTTGTGGCCAGGATGCTGGGC AGCTCTTCCTTCCCCCTCCCCGATGAGAATGACAGAAAAACAGGATTCACCTGAGCCAAA AGGCTTCCAGTTAGATCCAAGAGAGAATTTCCCGCAGTTTGAATTGGTTTGCTAAACAAC AAGGAAGGGCTGGGTGCGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAAGCCGAGGC AGGAGGTCTGCTTGAGCTCAGGGGTTCGAGACCATCCTGGGCAACATAGCGAGACCCCAT TTCATAAAAAATAAATAAGTAAATGAGAACAAGGAAGGACTGACGAGAGACGGTAGAACC TTCTGGTTTGGGCAGCTCTGCAGCTGCCATTCATCCTGGCCATAAGAATTCTTGGGGTGA ATAAGTTTGTCGCTGTTGGGCCGCATGAGATGCAGAATCGCCCACTCTCACCCCTGACAG AAACAGTTGTTTCCTTCAGGGAGCCTCCATCTTGGGAGATAAAGCATGTGTACATGGGAA CCCACTGGCCACACATTCTCTAGAAAGTACACAATGTCCCAGTGCCTCTAGAGCAAGCAC TTTGTACAGTCAGAAAGCAACAGGTGGTGGGGGCTGGAGTCATTCAGGAAAATGGGAGGC AGAGGAATGGCCTGAACGGCCCGATGCTAGGGGCTTCTGCCCCCAGATTCCCTCTTACGC ACACTCAGTGGTTGCCCTTCCCCTCCCTCCCCACAGTGCTGTGTCCCCTGCATGCTGCAG TGCTGGGGTCTGCCCTGGGTATAGCAAGGCCCACTGTTCCCTTATGCCCAGGGCTTCTCA CTGTCCTCTCCCAACACCCTCTCCCCCACTCCACTATTCCTAGGATCAAGCAGTGCACCA CCGTGAACTTGGAGGACCTGGTGGTGGCCCACCACGAAATGGGCCACATCCAGTATTTCA TGCAGTACAAAGACTTACCTGTGGCCTTGAGGGAGGGTGCCAACCCCGGCTTCCATGAGG CCATTGGGGACGTGCTAGCCCTCTCAGTGTCTACGCCCAAGCACCTGCACAGTCTCAACC TGCTGAGCAGTGAGGGTGGCAGCGACGGTGAGAGAGAAGCGGGAGGCCCTGGTGGGCTGA GGACCAAGAAAGGGTGGTGAGCTTGGGAGGTGGGAAAGGGGCACTTAGTGGCCCATGGGC AGAGGTGTGGGGCAGAGCAATCGGAAGGAAGGGAGCCACCCAGACCATCCCAGGAGGCAG GTCACAGGGCCCAAAAGGTACAGCACCCCCACCCCTCCACCATCACAGGCACACCAGGGC CAAGCCGCTAGGACCCTGGGTCTGACAGCTGGGCTCCCTTCCCTTGCAGAGCATGACATC AACTTTCTGATGAAGATGGCCCTTGACAAGATCGCCTTTATCCCCTTCAGCTACCTCGTC GATCAGTGGCGCTGGAGGGTATTTGATGGAAGCATCACCAAGGAGAACTATAACCAGGAG TGGTGGAGCCTCAGGTTCTGGAACACTCCCACGGGATGCGGGCTGGGGGATCTCTGCGAG TGTCTGCATGTGCCTGGGTGTCTGGATGGGCCAGGGTAGGGGAGTGTGTGTGTGTGTGTA CACTATTGTGTCTGTGCATATGATGTGTGTGGTGTAAGTGATGGGGAAAACGGGGTGATT GTGCACAGAGGCCCAGCACGCAGGAGAATGGGGTGCCCAGTATAGCCCCAAGTGCAGGGA CCCTCCCTCAAGTCAAAAATGCCACCCCCAGCCTGGTTCTCCCCAAACTCATCTTCCAAC ATATATTCCCACTCGACAGGCTGAAGTACCAGGGCCTCTGCCCCCCAGTGCCCAGGACTC AAGGTGACTTTGACCCAGGGGCCAAGTTCCACATTCCTTCTAGCGTGCCTTACATCAGGT AACGGGAAAGGCAGGAGGGCACATTGTGAGGGGCAGTACCCACAGCTTTGTGTTTCAACT GCGGCCACTGCCCGGTCCACAAGCTCTGTCAGTCAGGGCAGACCCGGGGGAGCCGGCCGC ACGGTGCAGGTGCCTGGGCCCACTCACACTGCCAAGGCTGATGGGTTTTTTCTTGAACAT TCTTTTGATGAGAGTCTGTACCATCCAAACAGTTGAACACAGAAACTCAACCTAATAATT GGCTAATGGTTACCAGACCTTGGTTAAGTAGTTAACATTAACCACGACTCATGGCTGGAT CATGAGCTCTGCACTGTTTTGTTTTGCTTTTAAAACAAGACTGTGATTCTTTTACTATTA TTGAACATTGTCTGCGATACAATTTGAATTGTACCTGGAAGCCCTTCTAGACACTAAAAT GTAGGATTGGAGATCGGTTAAGGTGGGAGGCAGGGTTGCTGGGGCAAGTTACAGTCACAG GCTGGGGTCAGACAGAACTGGGTTCAAACTCCGTCTCCATTACTTTGTTTCCTTGAGAAA ATTCCTCAATTTCTGTGAGCTTCCATTTCCTGACCTGTGAACCCCATTTCACAGGATGCA CGATGGCTAACTTCTTAGCATTCTGTCTCATACACAGCCTCCTCAGGGAGGGGTGGCCAG GACCCCACTATTCATCACTCTCTAGTGGAATGTAGCTGCACACTAGGTCTGCAGGTCACA TGGCCACAGATGAGTGTGCCCAATGCAGCCCCTCTCCTTCTGTGTGCCCCGGGAGAGCAC TTGCTGAGGGCTAGCAAGGCTGTTTGTGATCCGGGAGGCTCCCTGGGAGGCTGGGGGCTA GAGAGACCTCAGGCTGGAGTTCCAGGTGCCCCCGGGCTACAGGTAGCCCAGGCCACCCCC AGAGGGCTGTGGCTGCCTCTGGCCCTGGCCTCCCGTGGTTCCTGGAAGCCCAGCAAGGGC AGGGCCCATGCCCACCTTGCCTCCTGGCACCTGGGATGATGCCAGCACATCATCAAGTGC TAATAACTGATTGTGGGATGGATGAAGTCTGTCCCCAGAGTCCAGGAAGAGGGCATCCCT GGAGCACCTCAGATAGGCCTGACCTAGACGGTGCTCCAGAGATGACACTTAGGACAGGGC TCCCGCCTGCCTGCTGGAGTGGTCCCTGGGGTTCCCAGCCGGCGCTGGCTCTCACCCGGG AGCCAGCTGGTGTGATGGCTAGCTTCCCAGCTTAATGCAGACAATTCTCCAAACAGGGGT GGGCAAAGGAGACTTGGCTGCTCTAGAAAAACATTCCGGATTCTGGCCAGCAGCCTTCAC AAAGCACTTTTAGGAAAGACCAGGGAACTAGGTGGTACATGCTTGCACCCAGCATTCAAA GTGAGAGGCCTGTGCCACTGGCTCAGGACATTTAAAACCTCTTCAGACTTTAAGCTGGGG AGAATCCTCCAGCCTTGACTGGCAGATTTCTACCAGGGAATTCGTGATGCTTTGGATAAG ATCATGTAGGACTGGCTTCCCTGCCCAGACCACCCTAGTAGATCCACACGGCCCATTTGG CCACACCTTGCCTCTACTTGCATATACCCCAGGGATGGAGACCTCACTGCCTCCAAAGCC ACCTGCCAGATCTCTGAAGGCTCTGCCCTGACCCCATGGAGCAGGCCCTCCTGAGTTGTG GAGGCAGCTCTGTGGGTGGGAGGCATCTACACAGGCACGGCTAGGAAGAGGCTCAGACAA TGCTAAGAGCTGGGGTGGGGGAGCTCACCCTGATAGCTGTGGGCAGAGTTGGGGGGCCTT GGCTCTGCTGTGCGCATGTGACTTAGCACACATCACATGTGATGTGCAGAAGGGCCTGGG GCCCAGTGGCACAAGGCCCTCAACCAACTCCGCCCCGGGCCACGGCCTCGCTCTGCTCCA GGTACTTTGTCAGCTTCATCATCCAGTTCCAGTTCCACGAGGCACTGTGCCAGGCAGCTG GCCACACGGGCCCCCTGCACAAGTGTGACATCTACCAGTCCAAGGAGGCCGGGCAGCGCC TGGCGTGAGTGTCCTCCAGCCCTCCTTTGTTTCCATGCTCTGGCCTGCGCCCCTGGGCCT TGAGGGGTCTGTCCACTGGAGCTTTTGTGGGAACACTTGCCATTTTGAGCCGGGAACTCC CACCTGCAGCGTGGGCCAGGCCTGATTGCCATCTCCTTAGGCACCTGGAGCCCTGGGGCC CTGGGACAAGTTTCAGCTGGGAGTGGGTATGGAGAGTGGATGTCAGGTGGGGGCAAGAGG GGCCATGTCCTTCTGACTCTGCCTCCCTGTCTCATGCCTCCCCAGGACCGCCATGAAGCT GGGCTTCAGTAGGCCGTGGCCGGAAGCCATGCAGCTGATCACGGGCCAGCCCAACATGAG CGCCTCGGCCATGTTGAGCTACTTCAAGCCGCTGCTGGACTGGCTCCGCACGGAGAACGA GCTGCATGGGGAGAAGCTGGGCTGGCCGCAGTACAACTGGACGCCGAACTCCGGTACCGC CACCCACCCCACCTCCAGCCTTGGGTCTTAACCCCCTCCCCAGGCTGGGCAGCCATGCGG CTGACCTCGGAGCCTGGCCCTGCCCCGCACCCTTGCCCTGCCCTGCCCTGCCCTGCCCAT GCTGTCTCCTTGCTTCCCGCTCAGCTCGCTCAGAAGGGCCCCTCCCAGACAGCGGCCGCG TCAGCTTCCTGGGCCTGGACCTGGATGCGCAGCAGGCCCGCGTGGGCCAGTGGCTGCTGC TCTTCCTGGGCATCGCCCTGCTGGTAGCCACCCTGGGCCTCAGCCAGCGGCTCTTCAGCA TCCGCCACCGCAGCCTCCACCGGCACTCCCACGGGCCCCAGTTCGGCTCCGAGGTGGAGC TGAGACACTCCTGAGGTGACCCGGCTGGGTCGGCCCTGCCCAAGGGCCTCCCACCAGAGA CTGGGATGGGAACACTGGTGGGCAGCTGAGGACACACCCCACACCCCAGCCCACCCTGCT CCTCCTGCCCTGTCCCTGTCCCCCTCCCCTCCCAGTCCTCCAGACCACCAGCCGCCCCAG CCCCTTCTCCCAGCACACGGCTGCCTGACACTGAGCCCCACCTCTCCAAGTCTCTCTGTG AATACAATTAAAGGTCCTGCCCTCCCCATCTGAGTCTGTGTCCCTCACAGGGAAGCCAGG GACAGGGACAGGCTGCTTTCCTGCCTCCTGGCAGTCAAGTGGGTCCCGTTACTAGGTTTG TTCCTCCATCCTCCTTCAGGAGCCGGGGAGGATCCCCAGAGCTCTGCCCCAGCACCTCCT GGCGCTGGCGCCTGTCTTCCCTCCAGCCCAGGCAGCCCGCCACTGTCCTGCCACCGCAGG CAGCCCCTGTCTGGCCCAAGCACTGACCCACGCGGACTCTGGGAAGCAGACATCCTGGGC TGCTGGCCTCACATTTCCACTGGCAGTGGAGCCTTTCCCTGCTCCACAAATGGCCAGGTC CCCCCAGGGGAAGGCTTCCGGCTGTTATCGGCTGCCTCAGGGGGCGAGTACCTTGGAGGG CCTGCTTCAAGGAGGGTGCCCCCTGGAGGGCACACACCAGCCTAGTGCTTACCTTGGCTC CTGCCTGTACCAGCTCCATGACTCTGCTCGGGTGAACAGCCTTGGCTCTCAGACAGCCAT TCTAACACTGCCAGTGCAGAGGGGCCTCAGACGCTGGAGTGTAGCAGTGGCTGCACCTGC ACAGGGATTAGCTGCCAGCAGCCACCCTGCTGGCGTCCCAGCACACACCTCCTCACTCCC TGCATTGGAGGGAGTGTCATTTTAAGGGACATTTTTATGACTTTTATGTGTATGTTTATG TAGAAATTTGGAAAATACAGAAAACTGTAAAGAAAATAAAAGCCCTTTATATCAACGTCA AGAGATAA OMIM ID 106180