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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IFNLR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID163702
Official gene symbolIFNLR1
Full nameinterleukin 28 receptor, alpha (interferon, lambda receptor)
Aliases,CRF2/12,IFNLR,IL-28R1,IL28RA,LICR2,
Gene summaryThe protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.11
Gene position24513751 - 24480647  Map Viewer
Gene orientationminus
Gene size33105 bp
Gene sequence
OMIM ID607404