Entrez gene ID | | 164668 |
Official gene symbol | | APOBEC3H |
Full name | | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H |
Aliases | | ,ARP10, |
Gene summary | | This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants. |
Location | | Chromosome: 22 Locus: 22q13.1 |
Gene position | | 39493229 - 39500072 Map Viewer |
Gene orientation | | plus |
Gene size | | 6844 bp |
Gene sequence |
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OMIM ID | | 610976 |