Entrez gene ID | | 1659 |
Official gene symbol | | DHX8 |
Full name | | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
Aliases | | ,DDX8,HRH1,PRP22,PRPF22, |
Gene summary | | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21.31 |
Gene position | | 41561334 - 41601680 Map Viewer |
Gene orientation | | plus |
Gene size | | 40347 bp |
Gene sequence |
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OMIM ID | | 600396 |
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