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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CRISP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID167
Official gene symbolCRISP1
Full namecysteine-rich secretory protein 1
Aliases,AEGL1,ARP,CRISP-1,HSCRISP1D,HSCRISP1G,HUMARP,
Gene summaryFertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.3
Gene position49834218 - 49801970  Map Viewer
Gene orientationminus
Gene size32249 bp
Gene sequence
OMIM ID601193