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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DEFA5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1670 Official gene symbol DEFA5 Full name defensin, alpha 5, Paneth cell-specific Aliases ,DEF5,HD-5,MGC129728, Gene summary Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq] Location Chromosome: 8   Locus: 8pter-p21 Gene position 6914259 - 6912829  Map Viewer Gene orientation minus Gene size 1431 bp Gene sequence >DEFA5:complement(6902829..6904259):Length=1431 ATATCCACTCCTGCTCTCCCTCCTGCAGGTGACCCCAGCCATGAGGACCATCGCCATCCT TGCTGCCATTCTCCTGGTGGCCCTGCAGGCCCAGGCTGAGTCACTCCAGGAAAGAGCTGA TGAGGCTACAACCCAGAAGCAGTCTGGGGAAGACAACCAGGACCTTGCTATCTCCTTTGC AGGAAATGGACTCTCTGCTCTTAGAACCTCAGGTAGGAGACATCAATCTTGCACATCTGC AAAATCTAGAAAAAAAGGATTGGAGAAAGGATCTGGAGTCAAGTGTGGAAAGGTCTACCT CACTTGAGTGACTTTACTTAATCTTCCTGGACCTTGATTTTCTCATCTATAAATTAATCA GTGAGAACCAAATAAATCTAAAAGATTTTCTTTTTTCTAAGACTTTCAGTTCCAAGATAT TTCTGTGAAATTTGCTACTTTTAAGATAGAAAGAGCTACACTGACTAGTTCTTTGTAGAT CTAAATGGGCAGACTTAGTTATATAGAGAGTGTTTTACTTTGTCCATTGGAAAAGCTTTT AGAACCTAGAGAGGAACCTATAGGTGTGTTTTGATGTAGGCTAATAGGCTTGATTAAATC TTTCTACAATACATCCTTAGATCAAAACATCATATTGTGTCTCATACATATACACAATTA TTGTTTGTCAATTAAAACAAGTAAATATGTAAAATGTTAAAAAAAAAAAAAAAAAAAAAA AAAGGAGAGACAGAGAATGAAGAATTTGAATTTGGAAAGTCTTCAAAGACTCCTTGAGCA CCAAAGTATTTGGTCCATGACATTAGCATGCACAATGCGGCATTTCAGAAACTGATTCAG GTGCTTTAGGGAGCCTTGTTAGGACCTGGAAATCACACATGGAGGTCAAGATTAGGCGTG TGGATGAAGCAGAATGAAGAGTAGGTAACCCTGAGGTTGAGAGGTATATTGTTGGACCAG GGAGCAGGTAATAAATACATCCTGGATAGACTCACATGGGGAAAAAAACTATGATCTTGC ATGACTAACACATAGCTAGTAAGATTTCTTGTCACTTACGACAAAGACATGAATTTTCTC CATCCTAACATGACTGATACAGTGTCTCTTATTTAGACTATCTCAGTTAGTCTGGCTGTG CTTGTCCTTTTTCCCACCTCCCTCGCTGTGCCTGACCCTCTCTTCTTTCCACAGGTTCTC AGGCAAGAGCCACCTGCTATTGCCGAACCGGCCGTTGTGCTACCCGTGAGTCCCTCTCCG GGGTGTGTGAAATCAGTGGCCGCCTCTACAGACTCTGCTGTCGCTGAGCTTCCTAGATAG AAACCAAAGCAGTGCAAGATTCAGTTCAAGGTCCTGAAAAAAGAAAAACATTTTACTCTG TGTACCTTGTGTCTTTCTAAATTTCTCTCTCCAAAATAAAGTTCAAGCATT OMIM ID 600472