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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DFFB (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1677 Official gene symbol DFFB Full name DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) Aliases ,CAD,CPAN,DFF-40,DFF2,DFF40, Gene summary Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined. [provided by RefSeq] Location Chromosome: 1   Locus: 1p36.3 Gene position 3773845 - 3801993  Map Viewer Gene orientation plus Gene size 28149 bp Gene sequence >DFFB:3252477..3280625:Length=28149 CCGCTACTCTGGCCCTCAGGGTTGTGTAGTTTCCGGGGCCACGGCACCTGGGCACACCAG GTGGCGTCGCGCCTTTGCTTTCCTGAGCCTTCTGAGTAAGGTAATGTGGTGTCCGTGGGG CGACGCCTGCGCACAAGACCGCGTCGGGCCTCACTTTTCCCAGGCCTTCTGGGTAATGTA GTTTCCGGGATCGGCACCCGGCCTGTGCCAGCTTGCAGAGCTCACCAGGTGCAGACCCCT GCGGCCAGGGCGAGGACGGATCTGAGCAGCTGGGCAGCAGGTGCCACCGCCTGTGGGACC CAGAGGGCTTGAGGACATCTGCAATGCTCCAGAAGCCCAAGAGCGTGAAGCTGCGGGCCC TGCGCAGCCCGAGGAAGTTCGGCGTGGCTGGCCGGAGCTGCCAGGAGGTGCTGCGCAAGG GCTGTCTCCGCTTCCAGGTGCCCGCTGGGCTAGGCGGGGACGGCCCGTCGGGGAGGCGTG TGGGGAGAATAGGAGGTGCCGCTTTTCCTCTTCCAAAACGGAGGGTGCAGGCGGCGCCCG GGGCGGGTAGTTTTCGTTCGCCTCAGCCGCTAGGACCCCGGGCCCCCGCAGCCTGGGGTT CCTGAGCGTGGCTTCAGAACGCAGGGGGGTTGGGGGACGACCTGGATCACCCCTTCCCTC TTCCCACCTCTCGGGCAGGACAGCCCTGCATCAGAGCTAGGAGACCCGGGTAGAGTGCCA GGTACTGGCACGCGGGGTCACGGCTGCTCTGCCTGTCCGGCCTCAGCTTCCCCTTGAGTA ACATGAAAGGCTTGGCTAGGTGGGCTCTGCAGGCCCCTTCCAGCCCTCGCAGCTGGGGAT TGCAATCGTCACCTTATTCTAGGTTGGTTTTCTTTTTAGACCAGTACTAGGGTTACCAGG TGTGCATTGCCGGGGTCGGTGCGGGTGGGGTGGGAGTAGCCATAAAATGCCTAAAACTGA CCAGTGCAGAGTAACAGGGAACCGGACTCCAACAAATTAACAGTGCCACGTGCCGGTCAC ACTTGTGCACAGAGGCAACCAACCGTTCTCCTTCGTGTGCCAGCACCGCTCTGGCGGCTG TGTGCTGGGGATGGTGGTGTTCAGCTCCTGGCAGCAGGGAGGCGGCGCTGTCAAAGACAG GCTCTATTTGAAGCGCCCTCAGGAGCTCATTTAAAAAGGGTGAATCCTGCAGAGCCAGCA GTCACCCCCTGATGTATGTTTTTCCTGACTCTTCGTATTTTAGAACGGCCCGCAGTCAGG CGCCCTTGCTCCCGCTCCCTCATCCTTGCCTGGGCGTTGGAGCGACTGTGGCATACAGGC GGCAGCCTGAGCCTGCTTCTTTAAGCACAGCTCATTCCGGTCGTTTGTGAGGCCTGCAGA TGCAAAGCCCTCGTCTTGAGACCCTTCCTCCTCCTGTTGCTTCTCCCGTCCCTGCAGCTC CCTGAGCGCGGTTCCCGGCTGTGCCTGTACGAGGATGGCACGGAGCTGACGGAAGATTAC TTCCCCAGTGTTCCCGACAACGCCGAGCTGGTGCTGCTCACCTTGGGCCAGGCCTGGCAG GGCTGTGAGTGGCAAGGACTTTGGAGGTGGGCGGGAAGCTGGCACTCTCCGAGGTCCTGG GGGCTTAGCTCCAGGTGCCCATCAGGGTGGGGAAGAGTCCCCCTTACTGTGAACTCTCGG GTCTCAAGGAGGAAGCCCTCTGGAGGCAGAACTGGTCAGCGTCGCTTAGGTGGCAGAGTC CTCAGTCCTCTCGTTCATGAACCCAGCTGTTCAATTGGTCGTCTTTTTCTTCAAAAAATC TTTTAATTTTATTTGCGTTCATTTGAGGTGTCCTAGCAATTCCCAAGAGCAGAGGGAGGG CTTTGGGGTTGGGGCCTGCACAGTTTCATGGGGAAGGTGGAGCCAGGAAGAGATGCTGTT CTGTTCTGCTGGGCTGAGCACCCTTCTGGAAGGACGAGGTGGTGGTTCGTGGGATGCTCT CACATTGTTCTCGGTTGGTGTTTGCTAAGATGCTGTCCTCAGGGCTCAAGTTTGGGGGCA ATTGCTTTGAGAGGTGGTTCTTTCGGGGCATCTGTATTGAAGCCTCAGGACACAAAGTCC TGCCTTTCAGAACCAGCCGAATGCCAAGGTCTGCGCTTGTTTGACTCCCGTAAAAGAGAG CTTTTGGCCACTGGGGCAGGAGATGCCATCATGTGCCTTTACCTGGGAGGGTCGGCCAGT GTTGTGCAAATGGGGTCAGGCTCCAGGAGATGCTTCTGGCAGCCCAGGAAGGACATGGGT GCTCTGAGGGATGGAGCTGTGGCTCCTTGGCCTAAGGGGCAAAAAGAGAGAAGTCGAAGA GTAACATCCATGTGGCCACCTCCCCGGCTACAGTGTTGGGGGCTCCACTGTCAGCATTGA GGGGTGACGCCTCTGGTGTGTGCTCCAAGGTTGCAAACCCCCTTTCTCCACTGGGCCTTG TGCTTTTAGAGGAGGCAGCTGGAAAATGTATCACTGTGATGCCCCCTGGGGTGGCCCCTG CAGGAGGTGGGGGCTGGGCAGGGGTATGCTCAGGGTATGCCTCACCTTTGGATGTTATCT TTCTTTCCCATTTCAGGGCATAGTTGAAAGACAGCAGAGCACGTTGCTCTCTCTCTGTCT CTCCCTGCATCTCGCAGTCTCTGTCTCTCTCCTCTGTCTCTGTCTCTGGCTCTCTCTGTC TGTCTCTGTCTCTCTCTCTCTCTGTCCTTCCTTTCTCTGGCGCTTTATCCTCCTCTCTTC GCTGAGACCGCTAGTCCTCCTCCTTGTTAGACTTAAAAAAAATTTTTTTTCTTTTCTTTT ATGAAAACATTGAGATGGGGTCTCCCTCTGTTGCACAGGCTGGCCTCAAACTCCTGGGCT CAAGAAGTCCTCCTACTTTGGCTTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTG CCTGGCCAAAATATTTTTGTTTTATTTATATTTTGAAACTTTGTTGCCCAGGCTGGAGTG CAGTGGCACAAACCTTGCTCACTGTAGCCTCGACCTCCGTGTTTCAAGTGATCCCGTTGC CTCAGCCTCCCAAGTATCTGGGACCACAGGCATGCATTACCACGTCTGGCTAATTGTTTT GTATTTTTTGTAGAGATAGGGTTTCGCCATGTTTCCCAGGATAGTCTCACACTCCTGGGC TCAAGCTGTCCTCCTGCCTTGGTCTCCTAAAGTGCTGGGATTACAGGTATGAGCCACTGT GCCTGGCCTAAACCGTTTATTTAGAAATAATGACAGATTCCCAGGAAGTTGCACAGATAG GAAGGTCCAATGTACCTCTACCCTTTCCCTCAAAGGCAACATCAGATACAACCGTGGTAC AATATAAAACAGGAACACCGACACTAGTGCAATGTGCATGTTGTTCTGTCATTTCTCCCC ATGTAGATTCCTGTGACCAGCATCAGGGTCAAGGTACAGCCCTCTCCCATCCATCACTCA AGGTTCTCCCCTTTATAATCCTGCCTACCCCTGCCCACCAGCAATCCCTAGCCCGTAGCA ACTGCTGATATGTTCTCCATGTCTATAATTTTGTCATTTAAAGAATATTAGGGGCCAGGT GCGGTGGCTTACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACCTGA GATCAGGAGTTCAAGACCAGCCTGGGCAACATGGTGAAACCCCGTCTCTACTAAAAATAC AAAAATTAGCTGGGCATGGTGGCGGGCGCTTGTAATCTCGCTACTCAGGAGGCTGAGGCA GGAGAATCGCTTGAGCCCAGCAGGTGGAGGTTGCAGTGAGCTGAGATTGTGCCATTGCAC TCTAGCCTGGGTGACAGGCTGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATTAGG TAAGTGGAATCATAAAGTATGTGACCTTTTGAGATGAGCCTTTTTCACTCCACATAAGGC TCCCGAGATGCATGTAAGTTGTGTGTATCCATAGTCCGTTCCTTTTCATTGCTGAGTAGC ATTCCATGGTTTGGTTTTACCACAGTTTGTTCAACCATTCGCCTGTGGAAAGATATTTTG TTTGTTTCCAGTTTTTGACTATTACAAATGAAGCTGCTCTGGCCAATTATGTACAAGTTT TTCTTTTTTCTTTCTTGTTTTCTTTTGAGACAGGGTCTCACCCTGTCGCCCAGGCTGGAG TGCAGTGGTGCAATCATAGCTCACTCTAGCTTTCACTTCCTGGGCTCAAGCGATCCTCCT ACCTCCGCCCCTGAGTAGCTGGGACTACAGGGGTGCACCACCATGCCTGGCTAATTTTTG TATTTTCTGTAGAAACAGGGCTTCATCATGTTGCCCAGGGTGGCCTATAACTCCTAGGCT CAAGCAATCTACCCGCCTTGGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGCA CCTGGCCATCTTGACAGGTTTTTGCGAGATGTAGGTTTTCATGCCTCTGGGGAGAATGCC CAGGAGTACAGTGCTGCGTTGTGTGGTGTGTGTTTAGTTTCTGAAGACAAGGATGTCCAC TCTTGCTGCTTCTGTTTAACATGGTACTGCAGGGTCTAGCCAGGACATTTAGGCAAGAAA AATAAAAAGCATCCAGATTGGAAAGGAAGAAGTGAAGCTATTTCTATTTGCAGATCATAT GAACTTGTATGTAGAAAACCCTAAGGAATCCACTAAAAAGTGATTAGAACTAATCATCAA GTTTAGCAAGGTTGAAGGATATAAGATCATATGCAAATATAGAAATACACTTCCAACGAA CAATCTGAAAATGAAGCAGAAAATCATCCCATTTACACTGGCATCAAAAAGAATAAAATA CTTAGGATAAGTGTAACAAAAAATTGTAATACTTATATTCTGAAAACTGCAAAATGTTGT TGAAAGAAATTAAAGTTTTGAATAAATGGATTAACATCCCATGTTCATGGATTGGAAAAC TTAACATTGTTAAGATGGTGGGACTCCCCAAACTGACCTACAAATTCAACACAATCCCTA TGAAAATTCCAGCTGGTTTCATTGTAGAAATTGACATGCTGATTCTAATCCACAGTTCAT ATGGAATTGCAAGAGACCCAGAATAGCCAAAACGACTGTGAAAAAGAAGATAGTAGGAGG ACCCACATATTCTGATTTCAAAACTTAGTACAAAGCCACAGTAATCAAGACTGACACTGG TACAAGGACAGATATATAGATCAATGGAATAGAACAGAGCACCCAGAAATCTATGTATCT GTGGTCAGGATGCCAGGACCATTCAACGGAGGGGGAAGAGTAGTATCTTCAACAGATAGT GCTGGGACAACTGTATATTCACATACAAAAGAATGAAGTTGGACTCTTAGCTGGTACCTT ATACAAAAAGTACAATAAATGAAAGACCTAAATGTAAAAGTTAAAAATATAAAGCCCTTA GAAGAAAACATAGCGATAAGTCCTCATCGCCTTGGATTTGGCAAAAGATTCTTAGATTTG ACACCAAAAACATGAGCAGCAGAAGAAAAAACAGATAAATTGGGCTTCATCAACATTAAG AACTCTGGCCCGGGCACGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCCGAGAC GGGCAGATCACTTGAGGTCAGGAGTTGAGACAAGCCTGGCCAACATGGTGAAACCCCGTC TCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCAGGCGCCTGTAATTCCAGCTACT CAGGAGGCTGAGGCAGGAGAATTGCTTGAACCGGGGAGGTGGAGGCTGCAGTGAACGACA GCCCACAGAATAGGACAAAATAGTTGCCAATCATGTATCTAATACGGGACTTGCATCAGA ATATATAAAGAATCCTTATAACTTAATAGTAAAAAGATAACCCAATTAAACATGGGCAAA GGTTCTGAAAAGAAAGAAATGTCTCCAAGGAAGATATTCAAGTGGTCGTAAGCACAGGAA AAGGTGCTTGAGATCATCAGTCGTCAGGGAACTGCAAATCAAAACCACAGTGAGATGCTA CTTCACACCCACTAGGATAACAACCAGTGTGGGCGAGGATGCAGAGCGGCTGGAACCCTC AGGCCCCATTGATGGGAAGGGAAAACGGTGCAGCTGCTGTGGAAAATAGTCTGGCAGTTT CTCAACAATTACACAGAATCGCCATGTGACCCAGCAGCTCCACTCCTAGGTATGTACCCA AGAGAAATGAAAACACGTCCACACCAAAACTCGTCCGTGAGCGTTTACAGTAGCTTTATT CATAATAGCCAAAAGGTAGAAACCACCTAAGTCTCCAATGATGAACACTTGGATCAATAG AGTGTGGCACATCCATACAATGGAAGTACTCACCATGAAGAGGAATGAAACACAGCATGG CCGAGCCTTGAAACCATGCCAAGTCAAGAAGCCTGCACATACAGTAGGGTTCCATTCATA GGAAATACCCAGAACGGGGATGTTAGAGAGATGGAAAATAGATTAGTGGTTGTTTAGGGT TGGGGGTAGGGTAGAGGGGAGGGAGGTTGGTAGCTAAAGAGTATGAGGTTTCTTTTTGAG GTGGTGAAAATGTTCTGAAATTGACTGTGGATGTGGCTGCACAACTCTGGGAATATAATA AAACCCATTGTATTGTACACTTTATTTATTTTATTTATTTTTTTTGAGATGAAGTCTTGC TCTCTCCCCAGGCTGGAGTACAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCTG GGTTCAAGCGATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGCACCAC TGCGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGAT GGTCGCGATCTCCTGACCTTGTGATCTGCCTGCCTCGGCCTCCGAAAGTGCTGGGATTAC AGGCGTGAGCCACCGCGCCCGGCCTCTGAATTGTACACTTTAAATGGGTGAATTATAAGG AGTGTGAATTATATTTCAATAAAGCTACTTAAAATAAAGAAAAGAAACTGCCAAGTTGTG TGCTAGAGTGGCCGTCTTACCTTTCCACTGCGCAGTTTCTGTGCAGCCTCGCCAGCTTTC GGCGCTGTTGCTGTTTTTAATTTTAGCCATTCTGATTGCAGTGTGGTGATGTCTCGTTGT GCCCTTAATATGCATTTCCCTAATGGCTAACAATGCTGACTATCTGAATATCTTTTATAA AAACAGAGACAGGGTCTCACTCTGTTGCCCACGTTGGAGTGCAGTGGCAATCATGGCTCA CTGCAACCCTGAACTCCTGGGCTCAAGCGATCCTCCTACCTCAGCCTCCCAAGTAACTGG GACTACAGGTGTGCACCCCCATGTGCCGCTAATTATTATGATTTTTTTTAGAGATGGGGG TCTTGCTTTTTTTTTTAGAGATGGGGTCTTGGTTGCCAGGTTGGTCTCAAACTCCTGCCC TTAAGTGATTCTCCCACCTCGGTCTCTGAAAGTGCTGGGATTACAGGCGTGAGCCACCGC GCCCAGCCCTAAATATCTTCTTATGTGCTTATTTGCCATCTGTAGATTCTCCTTGGTGAA GTGTTTCTTCCTGTCTCTTGTCCTTTTTCTAATTGGCTTATTTATCTATTTTTTTACTGT TGAGTTTTGAAAGTCACGCCTCACCCCACAAACAAAATACCTGGACATGAGTTCTTTGTC AGACATGTGGTTTGCAAATATTTACCCTGTGGCTTTTCATTCTCTTAAGAGCATTTTTTT TTTTGCGGAGTAAGAGTTTTTAGTTTTGAGGAAGCTCAGTGTGTTGATTTTCTCTTTTAC GCAGTGCTTTTGATGTTAGGTCTAAGGACTTCCACCAAGTCCTCACTCCCCAGCATGTCC TCCTGTCTTCTTCTGACCCACTGATGTGATCGTGAGGCTTTTCTCATATGGTGGATCGCA CTGATCGATTTGCAGGTGTGAACCAGCCTTGCGTTCCCACTTGGCCGTGGTGATATTTCT TTGTGCATGTTACTGAGTTCTCTTTGCTAACATTTTGTTAAGGTCCTGGGTAGACTTTGC TTTAACTTCCTATTAAGAGCCTGCCCGGAGAGCTCGCTGCTTTAGGGAGTTGTGAAAAGG CTCCAGGAGAGAGTAGGAAAAGTGATCGGAAGGATCTGAAAGCAAGGTCTCCAGGAAGGG CCAAAGTGGGGGGCGTATGGTTTGGAGGGGAGGAGGCCAAATGGGAAAGCGGCCGTCTCT TGGTGCGCTTTCATCTGTCCTCTAAAGCACACCCTGCCCCTCCCTCCTCTGTCCTCATGC CGCCCTTGTGCGTGGTCCCCAGCTGTTGGTGTCAGGGCAAGGACAAAGACCCGGGACACC TCAAGTCTGAGTCCTGGTGATTGCCAGGCCCTGGGGAATGGGGGAAGATGTGGTCAGAGG CTCTTCTTGTGACCGGGGCAGGATGTGTCTTCTGCTGGACCGGCACCTTTTGTTTGTCCC ATTGGTGGCAGATGTGAGCGACATCAGGCGCTTCCTCAGTGCATTTCACGAGCCACAGGT GGGGCTCATCCAGGCCGCCCAGCAGCTGCTGTGTGATGAGCAGGCCCCACAGAGGCAGAG GCTGCTGGCTGACCTCCTGCACAACGTCAGCCAGAACATCGCGGCCGAGACCCGGGCTGA GGACCCGCCGTGGTTTGAAGGTGCGTGGGGGCTGCAGCTGGCAGGGGAGAGGCTTCTTTG GAGCCTGAGGTGCCAGAAGAAGTTGGATTCCAAAAAGCCCCCAGTGAAGGGCTGGCCTGT ACCCTCGTGGGTTGAGGTGGGGGACTTGGAAGAAAATGTGCTCATTTCCCAGCATTTCCC AGCCTCGTGGGAAAGGTACCCAGCAAGGACTCAGGTGGGGCCAGAGTCCAGGGCAGCCCT CGGATGGGACTTTTTATATTTTTATAGATATGTTTTGAGATGGAGTCTTGCTCTGTCCCC CAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACCGCAACCTCTGCCTCCCTGCACCCTC TGCCTCCCAGGTTAAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGC AAGTGCAACCACGCCCTGCCAATTTTTGTATTTTTAGTAGAGATGAGGTTTCGCCATGTT GGCCAGGCTGGTCTCAAACTTCTGATCTCAGCCTCCCAAAGTGCTAGGATTACAGGCGGG AGCCACCCCGCCTGGCCTATTATAATTATTTTAAAAATTGTGCTAAAGTACATATGACAT AAAATTTACCTTCTCAATCATTTTTTTAGTGCACAGGTCATCGGCATTAGGTACAGTCAC ATTGTATGCGGCCATCCCCACCGTCATCTCCGGAACTCCTTCCACCTTGCAAAGCTGAAC CCGTGTCCCTGTTACATCACTCCCCCTTCCCCCTCCGCCAGCCCCTGGCCACCACCATTC CGGTTTCTGTCTCTCTGATTTGATGACTCTAGGGACCTCATATGAATGCAGTCACATAGT ATTTGTCCTTGTGTAACTGGCTTATTGCACTCAGCACAGTGTCCTCAAGGTTCATCCATA TCGTAGCGTATATCAAAAGTTCTTTCTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAG GCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCCACCTCCCGGGTTCACGCCA TTCTCCAGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCT AATTTTTTTGTATTTTCAGTAGAGACGGAGTTTCACTGTGTTAGCCAGGACGGTCTCAAT CTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATCACAGGCGTGAG CCACCACGTTCAGCCAATTTCCTTCTTTTTAAGGCCAAATGACAGTCCACTGCGTGTACA TACCACGCCATCTATTCACTCCACTGCGTGTACATACCCCACTCTGTCCATTCACTCCAC TGCGTGTACATGCCACGCTCCGTCTGTTCACTCCGCTGCGTGTAGATACCACACTGTCTA TTCACTGACACTTGGGTTGCTTCCACCTTTTGGCCTGGCCTTGTAAGCCCATCAGAGGCG ATGCTGAGAGATTGTAGCCTTTTTGGGAAAGGAGGGCTTGAGGGCCAGGCAGAAGCTCCT TGGTGGTATTTGAGATGCTTCTAACAACAAAAACCAAACAGGGATGCTGTCTGTGTCGCC ATTAGAATACTTCTCAAGATGATGCAATCTGGCCAGGTGTCGTTGCTCACACCTATAATC CTAGCACTTTGGGAGGCCGAGGCTGGAAGACAGCTTGAGCCCTGGAGTTCAAGATCAGCC TAGGTAACAAAGTGAGACCTCATCTCTAAAAACATTTAAAAAGTGAGCCAGGTGTGGTAG TGCGTCCCTGTAGTCTTAGCCACTTGGAAGTCTGAGGCAGGAGGATTCCCTGAGCCCAGG AGGTTAAGGCTGTAGTAAGCTGTGTTCGTGCCACTGTACTCCAGCCTGGAGGACAGAGCA AGACCCTGTCAAAAAGATGAAGCAGTATGACCCTCATATTCTGCCCTGCTTGGCACCTGG GCTGGGCAGGACACAGACCCAGAGGCCCCTGGCCTGCCCTGTGGACTTGGGGGTCTTCTC GTTTTCCTTGCAGGCTTGGAGTCCCGATTTCAGAGCAAGTCTGGCTATCTGAGATACAGC TGTGAGAGCCGGATCCGGAGTTACCTGAGGGAGGTGAGCCTGAGTGAAGACCGGGTATGC TGGGCGGGTTTTTGAAGCCAGGCTCTGTGGGCTCTGGAAGCCTGTGGTCCTCACGATGGG TAGTTGGTAGGACCACACTCCGTGCTTGCGTGGATCTGGTGGGGCTGCTCTGGTGAGGGA AGCTAGCGCACGGACCCTGTGCCTCCTCCCTTCATGGGGGTGAACACCCATCGGGCCTTT TCAGCTGCACTTGAGGTCACGGGTTGGGGAGCGGGGAGGTGGTGGCTCCTGCCTGCCTCC CCTCCTCTCCTCCTCTCCCCCCGAGGCTTCTTCCTGGGCAGCAGTGGCAAGCGTCACGGC AGACACAGAGCCTGAGCTGTCATTTGCCCAACTGTGACCAAGGTCAGCAGGTGCTACAGG GATCTGAGGCCCTTCCCATGAGCCCATCCTTGGTCTGCAAACCTCTCCACCGCTCCCTCC TCCCTCCCAAAGGTGGAGTCAGCTCTGCCCTCATTTCCATCCACCCCATCGAATGTGGAT TTCCTCATCACATAGCATGACATGCCACGCTACACCATACCACACCATACCAGACCACAC CACACCAGGCCACACCACACCAAGCCACACCACACCAGGCCACACCACACCACACCACGC CACACCACACCAGGCCACACCACACCAGGCCACACCACGTCATTCCACACCATGCCACAC CGCATCATTAGCACATGGAGGGTGCTGTGGAGGCCCCTGCAATGGGTGTCCTGTCCTAGT GCTGCCCTGCGTGGTCGGCCCCCACGCCCTCGGCCCACTCCTCTCTGTGGCACAATTGCT AATGCTGCACTGCACCCCGTTTTTCTGCATCTCTTCGAGGTCCTGGCGACTTGCCATGTT CCCTTGCATTTCCCAGCCTGCTCCCTGTAGTGGAGCTAACTGATCCTGATACTCTTCCCT GCAAGTGCAATGACCAGGCCCTTCCACGCACCACTGCCTGCCTGACCAGGGTGGGATGGC CGTGCCTGCCTGACTTTATTAGCTCATCTTCTTTTTTGAGACGGAGTCTCACTCTGTTGC TCAGGCTGGAGTACAGTGGTGCAATCTCAGCTCACTGCAACCTCTGCCTTCCAGGTTCAA GTAATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGTACCACCATGCCC AGCTAATTTTTTGTATTTCTAGTAGAAATGGGGTTTCACCATGTTGGTCAGGCTGGTCTC AAACTCCTGACCTCAAGTGATCCGCCCACCTCGGCCTCCCAGAGTGCTGGGATTACAGAC GTGAGCCACCACACCCAGCCTGTTATCTCATCTAAGTCTCACCCAGCCTGGGGGCTGGTG TGGTTCCCTCCATTTCACAGGTCAGAGTCTCCCAGGGTGGGACAGCCCAGCAGTGGCCGA GAGGCCACGTGAACTCAGACCCTCTGACCACAGGACTGGGCTTGGGCAGGGTCTCAGAGG GCCATGGAGTGAGATGGATCGAGAGCCAGTGCGGGTTTTGGGGCGCTGTGCACCAGGCTC ACCGACGTTCCTTGGTTCCTCCAGGTGAGCTCCTACCCCTCCACGGTGGGTGCGGAGGCT CAGGAGGAATTCCTGCGGGTCCTCGGCTCCATGTGCCAGAGGCTCCGGTCCATGCAGTAC AATGGCAGCTACTTCGACAGAGGAGCCAAGGGCGGCAGCCGCCTCTGCACACCGGAAGGC TGGTTCTCCTGCCAGGTGAGCTGTGTGCCCTTTATCCTGGGGCCACCCGGCTGGCCTGTG GAACACAGCCCGCCTGGGGCGAGGCGGGTGGGGACCTTCAGCCCTTGCCCTGCCTGGGCA AAGCCTTGTGAAGAGGTACAGCCCTCACATTCCCAGGGAGGGCGGCAGTGTCTCAGCCAG TGCCTCTCAAGCTGCAGTGCACACAGGAATCCCTGGGGAGCTTGCAGAGGGCTGCAGGGC CCGCCCCAGGGCTTGTCTCGGTAGTGCTGGGCGGTGTCTTAGTCAGCCCCGGCTGCCATA ACAGATGACCCCTGCTGGGGAGGCTGGAACGGCAGCTGGTTACTGCTCATAGTTCTGGAG GCTGGAAGCTGAGATCAGGTCCGCACTCCCCCGCTGCCTTCCCAGGTGTCCCTGCTGCAC CGTGCTAGGCGTGGTCTGGCCTTTAGTGGTGATGCATCTGTGTCTCTGGCGAGTCCTGGG CACACCCCTCCCCCTCCCATGGTGTGGGGAGCAACTTGAGGCGCCTCTTGGCGTTTGCAC ACTGCAGTTGCATTCCCGGTAAGGTCCACTGATGCCCGTGATCTTCCGAGTGCCACTCAG TGGGTCCAGCAGCAGGGGCCAGGTGGTGGGCATGGCCTGCGGTGCTTCTTCCCATGGGAC AGGGCTCCTTGCTGCTCCTGCCAGGCAGATCCTTCTGGGGTGATGGGCTCTGGCCATAAA AACGCTTCTTCCAAGTTAGCTTAACATTTAGACTTTGCAGTGCGCTCGCTCACCACTCAG TGAGTACTTACTTTGTGCCTGGCACTGTGGGAGGGGTTGGGACACAAAAATGAAAAATCC TTCATCCCTGATGGCAGGGTGAGTCCTGCACAATGGAAGGTGAAAGACACATAAATGAGC GAGACAGAGGAGGCCAAGGGGCTGCAGGAGCCGCAGCCAGCATCCTGGGAGCCAGGGCCA GTCAGAAGCGGCCCCAGGGAGGGGGTGGGGCCTTAGAGCAGGTTGACTGATAGGTGGGGG TGCAAGAGTGAGCTGGGAGGGACCAGGTGCTCCGGGCATGGCAGTGGGAAGCAGTGGGCT CTGCTGGGGAGGCTGTGAGTCCCCAGGGTGATGGGGGCACAGAGTGCAAGTAGGCACTGG GGCTCCCGGCACGTGCTCTGCAGATGTCTGTTCACGAATGAGTGTGTTGAGTGCTGGGCT GCGGACCACAGGGAAGACGGAAGCTGTGGCCATGGCACCTTCAGTGAGGCAGCCCTGCCT CTGCATTGGGATCACAGGGAAACATCAGGAAGCCGCGGGCAATGGCTGGAAAGGGAGCCT CTGGGACATGGGTCCTTGCTTCTCACGCGCTGGTCCTGCCCTGGCAAGTCAGTACCTTCC TGGCCTCACTTCCCATGAGGTGGGGGTGCTGGTGTGTGATCACACGGGTAACAGTGACAA TAACTACCTTGTCCTCTTTGGGAACTCAGAACATATTGTTAGGGGTAATGAGGGAAAAAG AAGGATCTGATTCCAAAGGCAGAGCTTTTTTTTTGTTTGTTTGTTTGAGACGAGTCTCGC TCTGTCACCAAGCTGGAATGCAGTGGTGCGATCTCGGCTCACTGCAACCTCTGCCTCCCA GGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCCGCCAC CATGCCCGGCTAATTTTTGTGTTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGGCT GGTCTGGAACTCCTGACCTCAGGTGATCCACCCACATTGGCCTCCCAAAATGCTGGGATT CCAGGCATGAGTCACCACCGTGCCCGGCCAAGGCAGAACTCTGAATCTCCCTAAAGCAGT ATACCCTGGAGCAGGGACCAGCCCCCACGGGGTGCGTCTCTCAGTAAGATCACCTGACTT GGTGTATTAGGCCATTCTCGCATTGCTATAAAGAAATAGAGAGTGGGTAATTTATAAAGA AAAGAGGTGCAATTGGCTTACGGTTCAGCAGGCTGTACAGGAAGCATGGCGCTGGCATCT GCTCAGCTGCCGGGGAGGCCTCAGGAAACTCACACTTGTGGTGGAAGGGGAGGCAGGAGC AGGCACATCTCACGTGCGGGGAGCAGGAACGAGAGAGAGATTGAGGGGAGGGTGCTACTT TTAAGCCAGATCTCAGGAGGACTCACACTGGCGTGGGCAGCACCCAGGCGATGGTGCTAG ACCCTTCATGAGAAATCCACCCCCAGGATCCATCACCTCCCACCAGGCCCCGCCTCCCAC ACTAGTGCTGACATTTCAACATGAGCTCTGGGTGGGGCTGCACGTCCAAAGCATGTCACT CGGTGACTGAGACTGTATGAGACTCACTTCTGGCCGGGCGCGGTGGCTCAACGCCTGTAA TCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAAGAGATCGAGACCATCC TGGCCAACAAGGTGAAACCCTGTCTCTACTGAAAATACAAAAATTAGCCGGGCCTGATGG CGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTCAACACGGG AGGCGGAGGTTGTAGTAAGCCGAGATCGGGCCACTGCACTCCAGCCTGGCGACAGAGCGA GGCGCTGTCTCAAGAAAAAAAAAAAAAGAGACTCACTTTCTGGCCTTCCCTCATTGTCTT TTGGCCCCCAGGGTCCCTTTGACATGGACAGCTGCTTATCAAGACACTCCATCAACCCCT ACAGTAACAGGGAGAGCAGGATCCTCTTCAGCACCTGGAACCTGGATCACATGTAAGCTC ACAGAGCGAGGTTCAGACCCACGAGTGCCTGCAGGGCCCTGTCCCTGCCGTGGCCCTGTC CCTGCCATGGCCCTGTCCCTGCCACGGCCCTGTCCCTGCCACGGTGTTGCCTCCTTGGGT TTCAAGGGCTGCACCCGTGTTACAGCCCAGGGAAGGGGTACCTGATGGCAGCATAGGGGG CTGCTGAGTGGGCACACACCATTCCCTCCACTGTCAGCATGTGTACCTGACCCGGAGCCA GCCCTCCTGTCCCCTCCAGTCCTCCCTGTGGATGGAGCTGGTGGGCAGCGTCCTTCCCCA GAACACAGGTCCCAGCCCTTGGCTGTCAGAGGTTCTGAACCTCTGTGAGTTTGAACCAGG GTGAGCTCAGACAGCGGGAGCTCCTGGTGTTATGATAGGTAAGGGTGTTTTTCCCTTTTT CTTTTTCTTTTAGAGATGGAGTCTTGCTCTGTGGCCCAGGCTAAAGTGCAGTGGCAGGAT CATGGCTCACTGAAGCCCTGAACTCCTGGCCTCAAGCAATCCTCCTGCCTCAGCCTCCTG AGTCGCTGGGACTACAGGTGCTCGCCACCATGCCTGGCTGGCTTATTTTGTGGAACCAGC ATGAGCAGAAGTCTCAGCAGGCAGGAGTGTTTCACAGCCGTACGAGCTCTATGGCTCTAA CAAATGGGCAGGATGGAAAACTTCATTCTTTTAAACTGAGATGCATTCCTTGAATATAAT TGTAGCCTTGCCCTTGCTTTTTGAAGACAGAAGCCTTCAAATGCCCTTAAAATGGCTGTA CAGGATGAGCATCCCTAATCTGAAAACCTGAAATCCGAAGTGCTCCAAAATTCAAAACGT TTTGCGACCAACATGACGCTCAGAGGAGATGCTCATCCGGGCATTTAGGATTTGGGATTT TTTTTTTTTTTTTTCTGAGATGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGAT GTGATCTCGGCTCACCGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTACTTTAGCT TCCCCAGTAGCTGGGATTACAGGCACGTGGCACCACGTCCAGCTAATTTTGTATTTTTAG TAGAGACGGGATTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATC CGCCCGCCTCAGTCTCCCAAAGTTCTGGGGTTACAGGTGTGAGCCACTGCATCCGGCCAG ATGTGGGATTTTTTTAAGGATGCTCAGCTAGTCAGTATAATGTAAATATTCCAAAATCCT AAAAAAATCCCAAATCCAAAACACTTCTGGTCCCCAGCATTTCAGATGGGGACATTCAAC CTGTATTGCTTTCGGAGTGAGATTTTTTTTTAAAGTATGTAAAACACTATGGTCATAGTT GAGCTTTTACCCTGTCCATACTCAGCCTCTACACCTTGCCCCGAGGGAAAACACTTGTGA AAGGTGTGTGTGCCCTTCAGAGCCCTCTCACTGCACCTTTACCACAAGCGTGTGAGTTTA TCATGTACATACATGGTGGCCCACGCTGTCATCTGCAGAGCCGTGTAGCTGCACCTTTAC CACACGCGTGTGAGTTTAACATGCACGTACGTGGCCTCCCACGCTGTGGTCTGCAGAGCC GTGTAGCTACACCTTTACCACACGCATGTGAGTTTAACATGTACATATGTGGCCTCCCAT GCTGTGGTCTGCAGAGCCGTGTAGCTGCACCTTTACCACACGCGTGTGGGTTTAACATGC ACATACGTGGTGGCCCACGCTGTGGTCTGCAGAGCCGTGTAGCTGCACCTTTACCACACG CGTGTGGGTTTAACATGCACATACGTGGCCTCCCACGCTGTGGTCTGCAGAGCCGTGTAG CTGCACCTTTACCACACGCGTGTGGGTTTAACATGCACATACGTGGTGGCCCACGCTGTG GTCTGCAGAGCCGTGTAGCTGCACCTTTACCACACGCGTGTGGGTTTAACATGCACATAC GTGGCCTCCCACGCTGTGGTCTGCAGAGCCGTGTAGCTGCACCTTTACCACACGCGTGTG GGTTTAACATGCACATACGTGGCCTCCCACGCTGTGGTCTGCAGAGCCGTGTAGCTGCAC CTTTACCACACGCGTGTGAGTTTAACATGCACATATGTGGCCTCCCATGCTGTGGTCTGC AGAGCCGTGTAGCCGCACCTTTACCACACGCATGTGAATTTAACGTCTACATACGTGGCC TCCCATGCTGTGGTCTGCAGAGCCGTGTAGCTGCACCTTTACCACATGCGTGTGGGTTTA ACGTGCACATACGTGGCCTCCCATGCTGTGGTCTGCAGAGCCGTGTAGCTGCACCTTTAC CACACGTGTGTGGGTTTAACGTGTACATACGTGGCGGCCCACGTTGTCGTCTGCAGAGCC GTGTAGCTGCACCTTTACCACACGCGTGTGGGTTTAACATGTACATATGTGGCGGCCCAC GCTGTCGTGTGCAGTGTACCTGTTCATTGCATGCTGTGCTTAGATTCGGCATATTCATTT CAGCAGGTGCAGAACACTTCACTTTTTGAATAGGCTCTAATTTTAACATCTTTCCATACT GGGAGGCATTTAGGTTATTTCTAATTTCTCATCATTATAAAAATCCCTGGGATGAACACT CTATGGAATGAACCCATATGGTCTGGTTCCGTGCTATTTAAAGTGTGGTTACTTTCAAGC ATTAGCAACATCTGGGAGCTGGGAATTCAGATTCTCAGGCCCCATCCAGACATAACCCAG GTGCCTGGGGATTGGGGTGTGCGTCCCAGCATGGACAAGATGCCCCAGTGTCTGAGCTTG AGTCCCTCTAGTGAGTGTGCTGGGTCCTAATGACACCTCTGTTCCCTCTCTGAGCCTGGC CAGGCTGCTCTCGAGTGTCCCAGCCTACACACTCGCCATCCGTGTGAGTTCATGCTTTCC CGGGTTCTTGCTGACACTTGGTGTCATTGTACTTTTTTGCATTTTCCCAACCCGATAGGT GAGACACAGATTCTCTTTCTCTAATTTTCATTTTCCTGATGACTAGGAAGGTTGAGCTTC TCTTTCCACGTCTGTGGCCGCTTGTGTCTTCTGTGTTTCTTTCCTTTGCTCGTTCTCTCT TGGGCTATGGTCTTATTTGTGGGCATGCTTTACACATTCTGGATACGTTAATCCTATGAT ATCTTTTATCACAAGTTTTATTTATTTATTTTTTGAGATGGAGTCTCACTCTGTCGCCCA GGCTGGAGTGCAGTGGTGTGATTTCGGCTCACTGCCACCTCCACCTCCTAGATTCAAGCG ATTCTTCTGCCTCAGCTTCCCGAGTAGCTGGGACTACAGGTATGCACCACCACACCCGGC TAATTTTTGTGTTTTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCAA ACTCTGACCTCAGGTGATCTGCCCACCTTGGCTTTCCAAAGTGCTGAGATTATAGGCATG AGCCACTGTGCCTGGCCCACAACAAGTTTTCAGTGTTAATGTGCTCAGATGTTCCCTTTG TATGTTAAGAAATCCTGCCCTACCCTGTCTATCCGAAAGAGATTCTCCTACTCTTTTCTC TGCTGTTTGCTGGACCCCTTGCCACATGCAACAAGTACCCAAAAATGTTTTCTCCCCGCC ATCCAAATGCTCTTGTCCTTTTCAAGACCATTGCAGGTGGGGACATCAATCTAGGGGACA CAATCAGCATTTACAGAATGAAATAGGCCATCCTAGAACAGAGTACAGATGAAAATAGCA GAAGGGACAGCGTGAGTCAGAGGAATGTTTCACCAAGTGTTTGCTGCGGTTATATTTTCT CTCACGCTTCCTAAATATGTATACTCACACACAGATAAGTGTGTTGGGTTTTAATTAAAA ATGTAGTTTTCAGCACCGGTCTTCGGAAAGTTGCAGAGACAGTGGTCTGTTTGCCACAGG CCTGTCCTGACGTTTGTGGGGGTTGACACCACGTGCCACATGTTTAATTATTTAAGAATT AAAAGCTAATGAACAATGAAATAAAATGCATGCTGTCCCCCTACCTGGACTTACGTAGCA TCATGGCTGGGAAGGTTCGAGAAGAATTTGCAGGTCTTCCCCAGTTCCGGGATGTGCACA GCAGTGGAGCCTAAACATGGCCTGCCACCTGCTGCCTGCACCTTCTCTTCCCACCCTTAG TGCCACCTCACACCAGGGGCCTGCACAGAGAGCGTCCAGGCTTGGAACACCTTCCCTCTC GGGCTGAAGGGCGCGGGCCCTGGGGCTCAGCCTGTCCGAGGAAGACGGCCTGGCCCAGAG CCCATGCGGTTCAGGGGCCCCTGGGCGGAAGGTGGCACGAGGAGCGTCCGTGTGGGCTCT GGGTGGACCTGACTCCTCAGCCCAGAAGAATCCTGCCTCCCGTGGGAGGGCTGTGGCGGG TGGGGCCTGGAAAGCTCCCCTTTCCTGGAGCCCTGGGGACGTTTCTTTTAACACCATAGC GGGGTCCTCATGGCCTGTGTGAGCCCTGCCGCTGGGGAACTTTCCTTTCTGTCTCATCAC AGCTGTCTTTGGCCGTCTTTGGCCCTTTACTTCACTTTATTAACGTTTGCTTTTTTGTAA AATTTATTCCTACCTTCTACCTTTGTGGGTTTCTTCTTGCTTATTCATTTGTTCGTGTCT CTTTTGTATCTAATCTATACTTAAGGTAGTTCCTCCTAGGCTGCATGAGTTGTGTCTTGG GAGTTCAGTTTTTTTTTTTTTTTTTTTGAGGCAGAGTCTCACTCTGTACTCAGGCTGGAG TGCAGTGGCATGATCTCGACTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGGTTTTTCA TGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCGTGCCACCCCGCCTGGCTAATTTT TGTACTTTTGGTAGAGACGGGGTTTCACCATGTTGGCCGAGCTGGTCTCGAACTTCTGAC CTCAAGTAATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATCACAGGTGTGAGCCACCG CGCCTGGCTGGAGTTGTTTTGAGACTGAATGATTTACATTATGATTTTGTTTTTGATCCA TGGATTTTACAGAAGTCTTTTTAGTTTCCGAGCATGTTTTCGTGTTTGTGTTCAGTGTCT TGTGTTCCTGCCTGCCTTTCGTTGTGGTCTGTTTCCTTGTAACTGGTCAGCGTTTGTAGA TGTTCATAACACTCAGCACCTCAGTTCCACTGTGCCGGCTTTCTATTCTGTGCCGGCTTT CTATTCTGTGCCGGCTTTCTCTCGGTCCTGTGGCGTTTCCACCCCTTTCCTTTGGCCTTT ATGTGCCATTAGGTTTGGGCTTATCTCTTGTTAGCCAAGGGTAACAGCCTTTCGTCTTCA TCTAACCTGAGATTCTGTCATTCAGCCAGCCGCAGCTTGAACCTCCTGCTGCAGGTGTTG TGACAGCTGCTGTCTCCTAGAATGTGACTCTGTGGGGTCCCTCGCTCTCAGCTGTGTCCC CAGTGTGTGGGACGTGGGACAGAGTTTGGCCATGATGGCTACTCAGTGAATATCTTTTTT TTTTTTTTTGAGACGGAGTCTTGCTGTGTCGCCCGGGCTGGAGTCCAGTGGCGCAATCTC CTCTGACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTTGTGCCTCAGCCTCCAGAGT AGCTGGGATTACAGGCACCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAATAGAGAC AGGGTTTCACTATGTTGGCCAGCCTGGTCTCAAGCTCCTGACCTCAAGTGATCTGCCCAC CTCAGCCTCCCAAAGCGCTGGGGTTACAGGCGTGAGCCACCACGCTGAGCCCACTCAGTG AACCTCTGTTGACCGTTTTGTTGAGTGAATACAGATTGGATTTTAGCTGCTTTACTCTGG GTTTGTACCCACCATGCCGCATCTTCACTTTCTTCTGGTCTCTTGTGTGCCTTCTGTTGA CTTACTTGAGTTTCCTTCTTTCCCTTGCCCATCACCCCACCCTTTTGTGGTTTGGCGTTC ATGGTGTCCCTAATGTTAGTGATACTGGAAGACGGCACTGCTGCTGTCCCCTCTCCCGGG CCGGCCTCGCTGTGACCCTCTGCGGTATTCTTTAGTGTTCGTGTCTCACCTTATTTTAAT CCTGCACAAAATGCTGGTGTGGTTTTATGGCCAACACTTCCATTTATTTATCAACAGATT CACCCGTGTCTGTGTTTGCCAGTGCTTCTTGCATCTCATCTCTGGGTTCAATTTCTGATT ACTGATGTGTAGCCCTTAGTGTTTCTTCCACGAGTGGCTGTGAGGGGTAAACTCTACTCA GCATTTGAAAAGGTCCGTTCAACTTCCACTCTTGAGTAATTATTTAGTTAGTACTGAATT CTAGGATGACAGATACCTACCTTCAGTACTTTGAAGAATAACTCCATTGTCTTCTGGAAT CTGTGAGAAATCTGTTGGCAGCCTAATTTTCTGCCTTTTTAATGGTAGTTTTAGATTTTT CTCCTCCTCTTGGAAAATGATAAGTATCTAGGTAGAGCTCTTTCTTTTGGATTCTGCCTG GGACTTGTATTCCTTGTGCTGAGGACACACTTTTCTTTGGTTTTGGAAAATGCTTCTGCG TTGATGAGGTGTGGCTTCTCTTTGATTCTGCCTGTGCGGTTTTCCGGGAGCGCCTGTTAG CTGTGTGTTGGACCTTCTCATTCTGCTCTCCTCATGCTGTGCCTGCGTCTGGGCTGCTGT CTCACTGGGACTTTCTGCTGTGGACTCCATCATGTTCCCCAAGATTCGTATGTTGAAACC CTAATCCCCAGTGTGACTGCATCAGGCGATAAGGTCTTTGGGAGATAATGAAGGTCATGA GGGTGGGGCCCTAATCCACTAGGACTGGTGTCCTTAGAAAATGGGAAAGGAGCTCACTCT CCCTCTGTCTCTGCCACGTGGGGACACAGCAAGAAGGCAGCCATCTACCAGCCAGGAGGA GAGCCCTTACTAGCACCCGGCGTGCGGGCACCTGTTCTTCCAGCCTCCAGGACTGTGAGA GAGTAAATACTCAGTCTGTGGTATTTTCCTCTGGCAGCTGGAGCACACTAAGACACTCCT GTATTGTTCAGGAATTCTCTCTTCAGCTGTTCATATGTTCATTCTGTCCGCTGAGTACAT GCTTCCTTTTTTGGGTTCCTAAAGAGCCCAAAAGAAGTGCTTTTGGGTTCTTCATAAAAC GAGCCTTTTTTATGCCAGTCTGGTTTCATTATTTCCATTTCTTTTTAATCACTTTAATCA TTAATCATCCATTTTAAGCATATTTGTTTTACAGTCACATGCTAAAGCATTCAACCTTGC CCACAGGTCTGGCATTCGTTCTTGAGCCCTGGGAGGTAAACGCCAATGCCTTCAAATGTC CTGCCTGGTAGGAGTGTCTTTGTTCACCTGGGGGCCTTGGGTCACTGGATAGTTTAATGG CGTGATTTAGGATGGGGTCTTTGGTTCAGCTTGACCTCTAGAGGGTTTGAGGTGGAGGTT GGCCCCATGGGCCATCAGCCATGTCTGTGTGAGCCCCAGTAAAGGCTGGCACCCAGGCCT GGTGAGCTTCCTGGTTGGCAGTGTCGTCACAGAGGGCTGTGGAAGTTAGTGCTTGGGGAA GGTAGGGCTGGCCATGACCCCACAGGGAGGGGACAGCTGGAAGCTCTGGGATTGGAACCT TCCTGGACCGCCCCCTCTGTGCCTCTTAACCTTGGCTGATTTTCATCTGCAGCTATAAGA AACGATAACCTTGAGTCCAACGGCTCACTGGGGGATCTGCGAGTCCTTTCAGAGAGTTAT GGAGTCTGAGGTGGTCTCAGGGACCCCTCCCTGCTGTAGTTGGTGTCAGGAGTGAGGGTC CTTGTGGACTGTGCTGGGCTCCTGAAGGGCCTGTCACGTGGGCAGCCCTCTGCCGCTGCT GGGTCTGCCTCTCCTGCTGGTGGAGCCTTCTGCTGCTGTGTGTTTGGGCCTGGAGCTCGC TTCAGTGGGAAGTGCTTCCCGTAGGCCTCCTCTGTGCTCCAGTGTGTCACGGTGCCTTCA GTGTGGCTCTGGTGGAGCCTTCTGCTGCTGTGTGTTTGGGCCCGGAGCTCGCTTGGGCCT GGAGCTCGCTTGGGCCTGGAGCTTGCTTTAGTGGGAAGTGTTTCCTGTAGGCCTCCTCTG TGCTCCGGTGTGTCACGGTGCCCCTTCAGCATGGCTCTTCGTGGGTTCGGATTTGATTCC TGCGGATGCCCAGGGTTTCCCTGTGACTTGGAAGCAACTTCCTGCCATTTCTTGCTTGTG GTTCCCTGCCTTGTTGGTCGTGTACTTTGGGCCGTACACCCTGCGTTCTGCGGATGACTG TGAAGGTGGGGACAGGAACACACTCCCGATGTCCACACCCTGTGTGCTCCCCTGCCTTCT CTCCCCACGCTGAATTCAGGCTTGTCCACGTGACACCAGTGAAGGCAACACTGAGCTAAC AGAGGCCTGCTTGTGTGGGGGACTTGTCCCCTCTGAACACTGCCATGGCCATGTGAGGGA GCCTGTCCTGGCTCCTTCAGGATGGGGGAGGACAGGGGAGAAGGGCCCAGCCCTAGGCCA CCCTCCATCAGACACAGCCCCGGTGTGCACCAGGCAACACCAGCAGAAGGCCCCCCAGGC CAACCCCCGGAAGCCACTGCATTTTGTGGTGGCTGCTTCTGCAGCATTAGATAACGGGCT CAGTGGGTTTCCCTTCCTCTTGCCCAAGCCCCGGGCTCCACTCAAGCTTTTCTATCCCCC TTAATGGCTATGGCAGGGGTCTCGGTCCCACCTCCCTGTCTTTCTAGGGTCCCCTGGGCC TGTATCAGGGACTGGAACCCTGGTAGGCCCCTGGACCATAGCTTGCCTGTGTGCACTAAT TTCTCTTTGGTTTCTGGCAGCTGGGGAGCCCCTTTCTTTTGATCTCAACTAAGTATTTTA ACAAGGTGACTTTTGGCTGGGTGTGGTGGCTCATGCCTATAATCTCAGCACTGTGGGAGG CCAAGGTCAGGAGTTCAAGGCCAGCCTGGCCAACACGGTGAAACCCCATCTACTAAAAAT ACAAAATACAAATACAAAAATTAGCTGGGTGTGGTGGCGCACGCCTGTAATCCCAGCTAC TCAGGAGGCTGAGGCAGGAGAATGACTTGAACCCAGGAGGCGGACATTACCGTGAGCTGA GATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTTTCAAAAAAAAAAA AAAGGCGACTTTTGCTCAGCATTTTGTGGGTTGTAGGGAGAGGGGTCTGCACCAGTTTAG CTCACTCAACACCCACCATAAGCCCTCCTGGCCGTGGGGTCTCTAAACCCCACTTGTTAC TGCACAGTCTTCCAAATGGTTTATAAGTGAAACAACATCATGTTGTGTGTGTATGTGTGT GCGTGTGTGTTTGGGACAGTCTCACTCCAACCAGGCTAGAATGCAGTGGTACGATCTTGG CTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTTTCGTGCCTCAGCCTCCTGAGTAG TAGCTGGGATTACAGGCGTGCGCCACTATGCCTGGCTAATTTTTTTGTCATTTTTGTAGA GGTGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCACCC ACCTCATCCTCTCAAAGTGTTAGAATTACAGACGTGAGCCACCACGCCTAGCCTCATGTA GTTTTTTGTTTTCTTTTTTTTTTCAGACAGAATCTCACTCTGTTGCCCAGGCTGGAGTGC GGTGGCACAATCTTTCTCTCTGCAACCTCTGCCTCCAGGGTTCAAGCAGTTATCCTGCTT CAGCCTCCTGGGCAGCTGGGATTACAGGCATGCATCACCATGCCCAGCTAATTTTTGTAT TTTTAGTAGAGATGAGGTTTCGCCATCTTGGCCAGGCTGGTGTTGAACTCCTGACCTCAG GTGATCCGCACGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCT GGCCTCATTTGTTTCTTAAACAGATACGCATATATGCATATAACGGTATAAGATTAGGAT TGGAAAGATCAATAGCAAACCCTTAATAGTGATTACCTCTGAGGGGAAGGAGGGACATAA GATTACAAGTGGTATCAAAAGTGACTTCAGCTTCCTTTGTAAGGCTCTGTTTGTAAAACT TTCATGTTCTATCATGTAATTTTTTGGGGGTAAATGTATACGTAGATGAAACGTGGAGGC AGTTAAGCCAGTTGTTGATGGTGGGTGACTGTAAGTGATGGAAAGGTGGTTGACCCCCTT TATTTTCTGCGTACTTTTCAGTATTCTGAACAGTGACACGAGTCTTTTTTTTTTTTTTTT GAGATGGTGTTTTGCTTTTGTTGCCTAGGCTGGAGTGCGGTGGCGTGATCTTGGCTCACT GCAACCTCCACCTCCAGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGA TAACAGGTGCCCACCACCAAGCCCAGCCAATTTTTTGTATTTTTAGTAGAGATGGGGTTT CACTATGTTGGCCAAGCTGGTCTCGAACTCCCAACCTCAAGTGATCCACCCGCCTCGGCC TCCCAAAGTGTTGGGATGACAGGCGTGAGCCGCCGTGCCCGGCCACAAGTCAAGTTTTAA AAAGTAAGAGGAGCCAGGCTGCTTGCATCAGGCTCTGCTCAACAAACCTGGCCAGTAGGT GCGGCCGTGTGTCCGTGATAGCACTTAGGGGAATTTGTGAAGAGCTGTGACTGCAATACA CTGCTATGACCTGTTGCCTGTGGCACTGTGACCACAGAAAATGATGTCTCTAACCTTACT TTGCAGAATAGAAAAGAAACGCACCATCATTCCTACACTGGTGGAAGCAATTAAGGAACA AGATGGAAGAGAAGTGGACTGGGAGTATTTTTATGGCCTGCTTTTTACCTCAGAGAACCT AAAACTAGTGCACATTGTCTGCCATAAGAAAACCACCCACAAGCTCAACTGTGACCCAAG CAGAATCTACAAACCCCAGACAAGGTTGAAGCGGAAGCAGCCTGTGCGGAAACGCCAGTG ACACGTACACACCACGTCCTGGTCTTTGTTTGAGGCCTGACGTGGGCATCATTTTAACAG GTGCCTTTTTTGTTTTTTTGTTTTTCGTTTTTTTGGTCACTCCAGTAGCTCCTGGAAAAA ACCTTAAAAAATGTTTCCTCCAAATCTGATTTCATTACATTTCTGAATTGTTGGGGTTTT TTTTGTTGTTTTGTTTTGTTTTGTAGATGGAGTTTCACTTTTGTTGCCCAGGCTGGAGTG TAGTGGCGCGATCTCGGCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCAC GCCCGGCTAATGTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGT CTCAAACTCCTGACCTCAGGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATGACA GGTGTGAGCCACTGCGCCCAGCCTGAATCATTTCTTATACCTTCTGACAGCCCAACTTCC AGAGGACAGCTCTGGGGTACTCGTTGGATGTCTGTGAGTACCTGGTCATACGGGTCAGTA GGGATAAGAATTGTCTCTGGGCTGAGGAATTCTTCTGTTCTCTGGTTTCACCAGCGTTGG GTTTGCTCATGTAATGTGGTCACCATACTCAAATGGTGTCATGGCTGAAGTTGGCCACCT TGCTTGAGGGACAAGTTGTTTATGTATCAGCTCTCTGCTGGGTCTCCCTTTCCATGGCAA ATGGGCAGCTCCATCCTCTTGACTCTTCTAAATGCCCAAAAGAGGTGTCATGCTTTGGGG GTACGATGTTTATACTCCGTAAAGAACATACAAGGACATTCACTGCTGATTTTTTTTTTT GTTTGTTTGAGACAGGGTCTCACTCTGTCGCTCAGGCTGGAGTGCAGTGATGCAATCTTG GCTCACTGCAACCTCCGCCTCTCAGGTTCAAGTGGTTCTCCTTCCTCAGCCTCCCAAGTA GCTGGGATTACAGGCACCTACCACCAGGGCCAGCTAATTTTTGTATGTTTAGTAGAAACG GGGTTTCACCATGTTGGCCAGGCTGTTCTCGAACTCCTGACCTCAGGTGATCTGCCCGCC TCGGTCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCTGACCTGCTGAATTG TTTATAATGGCAAGAAATAGGAAACCCCCCAATGTCTGTTGAACAGCTATCACGTTGAAC CACGTGAAACTGCTGTTTTCTAGGCCAAAAATGGTGAGCGATCATTTATTTCATGATTCA ACCTGATACATTTACATAGTGCAAAACTGTGTCACAGTTTCAGGCTTTTATGAGGAAAGC GTTTCTGTGTAGAAACTGGAAGCTGTTCAGGGCATCGGCAGCTGAACCCTGCTCCGTTGG TCAGCGTTACTATCATCTCGGATCATATGGAGCTCATGTCAGCCGTGTGGGTGGCGGGTG CACAGAGACGGTCTGGAAGGAAACACGCGGATCTGAACAGCAGTAATCCTGGGGGATACG GGGGTTGGGCTAGATTACAGAGGGCTCATTTTCTACGTCATGTATTTTATGATACTTGAA TTTTTTGAAATGGGCATTTATTTTATAACATGTTAAAATGTACTTTTTAAATTAAGTCAT TTTGTAATATTTGAATTTTTACATTTGTTGTACAATCAGGAAAAGCAATAAAGATTTTTC AAAAATAGA OMIM ID 601883