Entrez gene ID | | 169026 |
Official gene symbol | | SLC30A8 |
Full name | | solute carrier family 30 (zinc transporter), member 8 |
Aliases | | ,ZNT8,ZnT-8, |
Gene summary | | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene. |
Location | | Chromosome: 8 Locus: 8q24.11 |
Gene position | | 117962512 - 118188953 Map Viewer |
Gene orientation | | plus |
Gene size | | 226442 bp |
Gene sequence |
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OMIM ID | | 611145 |
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