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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DGUOK (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1716
Official gene symbolDGUOK
Full namedeoxyguanosine kinase
Aliases,dGK,
Gene summaryIn mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p13
Gene position74153953 - 74186088  Map Viewer
Gene orientationplus
Gene size32136 bp
Gene sequence
OMIM ID601465