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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DHPS (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1725 Official gene symbol DHPS Full name deoxyhypusine synthase Aliases ,MIG13, Gene summary The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.2-p13.1 Gene position 12792677 - 12786534  Map Viewer Gene orientation minus Gene size 6144 bp Gene sequence >DHPS:complement(4049336..4055479):Length=6144 CTCTTGCGGAGACGCGCGCGTCGGGGTTTAACGCGTTTCTGGGCCGCCGTAAGCCCGGCC TAGGGGCAGCTTTGACTCGAGAGCCGGCTATAGGCGCATGGAAGGTTCCCTGGAACGGGA GGCGCCAGCGGGGGCGCTGGCCGCCGTGCTAAAGCACAGCTCGACGTTGCCGCCCGAAAG CACCCAGGTCCGGGGCTACGACTTCAACCGCGGTGTGAATTACCGCGCACTGCTGGAGGC CTTCGGCACCACCGGCTTCCAAGCAACCAACTTCGGGCGCGCTGTACAGCAAGTCAATGC CATGGTGAGGACCGGGCGGAATTTCTAGGGACGCGGAGGGGCGTGGCTTGTAGAACCAAC GCGGTACTAGACGGGGGCAGCGTTTCCAGTGGAGGGGATATGTCTTTTATTTGAGTTGCC CAATAGTTGGAGGAAGGCGGGACCTATTCTGGGCGGGAGTTTCTGTCCTGGGAAGGGGAT TTTGCACTCTGGTAGTTACATGCTGGTACGGTAACCTGAGGAGGCGAGGACTGATTCTTG GTGTGGGGGCGGGTTCTAGGTACATTTAAAGCTTTCTGGAATGGGCGGAGCCTGGGGCAA GACAAATTAAGGGAGGATATGGGAGGAGGAGCCTAAGTCTGGGCGGTTCTTGAATTTAGA TTTGCTTTTCCCAGCGGGGAAGGGACCGGATCTGAAAGGAGATGCTCTCTGATTCCTAAA AGGGTGGGGGCTGGCTGGGCGCGGTGGCGCATGCCTATAATCCCAGCATTTTGGGAAGCC GAGGCGGGTGGATCAAGAGAAGAGGAGTTCGAGACAAGCCTGGCCAACATGGTGAAACCC TGTCTCTACTAAAATGCAAAAAATTAGCCGGGCATGGTGTTGCGCGCCTGTAGTCCCAGC TACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGCGAGGTGGAGGTTGCAGTGAGC TGAGATTGCGCCACTGCACTCCAGCCTGGTGACAGAGCGATACTCTGTCTCAAAAAAAAA AAAAAAAAAAGGCCGGGCACGGTGGCTCATGCCTGTAATCTCAGCATTTTGGGAGGCCGA GGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCC CGTCTCTACTAAAATGCAAAAAATTAGCCGGGCATGGTGGTGCGCGCCTGTAGTCCCAGC TACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGCTTGCAGTGAGC CGAGATCGCGCCATTGCACTCTAGCCTGGGTAACAAGAGTGAAACTCCGTCCAAAAAAAA AAAAAAAAGGGTGGGGGCAAATCCTGAACGTGTGTCTTGAGATCTGGTCTGGGAAGGGGC AGAGTTTACACAGGAGATGTTCCTTGGTCCCCTGTAGAACTGGTCCTGTATCCCTGAATG TGCAGGGCCTGGGGTGAAATCTGTTTCTGGAGCCCACCTGGAGTCCTGAGTCTGGGATTT AAGGCCAGTGCTTAACTTGACTTGGCCCTTACTCACAGATCGAGAAGAAGCTGGAACCAC TGTCACAGGATGAAGACCAGCACGCGGACCTGACCCAGAGCCGCCGCCCACTTACCAGCT GCACCATTTTCCTGGGATATACATCCAACCTCATCAGTTCAGGCATCCGTGAGACCATTC GCTACCTTGTGCAGCACAACATGGTGGGGACCTGGTGAGGCCGTGGCCTTGGCCTCTGGG TCAATGGGCAATGCAGTTATTGATCGTTTAAGTGAGATGGGCAGATAGGGGTCTGTTATA AGCAGAGGAATAGAATCAAGTTTTGTTTTGTAGCAGAGCTCCCTCATAAGAGTCACTGGA CAAGGATGAGGTTAGAAGTTCTGCCCAGAATGAGGGCAGGGGCTTCCTTCTTGGGCCAAA TTCACTGCCTTGTGGCTGCAGGTGGACGTATTGGTGACCACAGCTGGCGGCGTGGAGGAA GACCTCATCAAGTGCCTGGCGCCCACATACTTGGGCGAGTTTAGCCTCAGGGGGAAGGAG CTCCGGGAGAACGGGATCAATAGGTGAGAACCCTGAGTGGTGTTGGGCAGGGGAGCTGGA CCAAGGGTCCTGGGGCCTGATGCCTACATGCCTCCTGTTCTCAGGATCGGAAACCTGCTG GTGCCCAATGAGAATTACTGCAAGTTTGAGGACTGGCTGATGCCCATTCTGGACCAGATG GTGATGGAGCAGAACACAGAGGTGGGGCTGGGGCAACCTGGAGGGGCCAGTTCAGTGGGA GTCAGGGGAGGCATGGCCTGAAGGTCACATCCTCTCCTAGGGTGTAAAGTGGACGCCTTC TAAGATGATCGCCCGGCTGGGCAAGGAGATCAACAACCCAGAGTCCGTGTATTACTGGGC CCAGAAGGTGAGGACCTAAGCGGGAGCAAAGTAGCCAGACTTTGGCATGTGTTAACTTAT TTCATCTTTCCAGCCTCCTGGGGATTCAGTACTGTTATTCTCAGCATCCTCACTCTTAGA TGAGGAGACTCAAACACAGATAGGCGTGGTAATTTTTTTTTTTTTTGAGACAGGATCTTG CTCTGTCACCTAGGCTGGAGTGCAGTGGTGTGATCACAGCTCATTGCAGCCTCAACCTCC TGGGGCCAAGCAGTCCTCCCACCTCAGCCTCTCGAGTAGCTGGGACCACAGGCACATGCC ATCATGCCCAGCTAATTTTAAAAATTTTTTGTAGAGATGGGGGTCTCCCTGTGTTTCCCA GGCTGGTCTTGAACTCCTGGCGTCAGGCAGTCCTCCCACCTTGGCCTCCCAAAGTGCTGG GATTACAGGCGTGAGCCACTGTGCCCAGCCAGGCTAGGTAATTTTGTCTGAAGTCACACA GATAACTAGTGGGGCCTCAGCATCCTTATGCTCCTCCCAGACTATCTCTGGAACAGTAGA GGCAACACTTAGCAACTCTCCTGGGGCCTGGCTCAGGGTCCCACACTCCCAGATGCTATA AAATAAGAGCTACCCACTCCCTTTAATTAGAGAATCAGAACCTGAAAAAAAAAAAAAAAA AGCTACATAGTCTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCGCCC AGGCTGGAGTGTAATGGTGTGATTTCAGCTCACTGCACCCTCCACCTCCCAGGTTCAAGT GATTCTCCCGCCTCACCCTCCTGAGTAGCTGGGACTATAGGCACCCACCATCATGCCCGG CCAATTTTTGTATTTTTCTACAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAAC TCCTGACCTCAAGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGGGTGA GCCACCACACCCAGCCTACTTACTCTTTCTTTTTTACGAGACAGGGTCTCATTCTGTTTC CCAGGCTGGAGTGCAATGGCACAATAATGGCTCACTGCTGTCTTGAGCTTCTGGGCTCAG TCGATTCTCCTGCCTCAGCCTGCTGAGTAGCTGGGACTACAGGTGCGTGCCACCATGCCT GGCTAATTGTTTTTGTAGAGATGGGAACTCACCATGTTGCACAAGCTGGCTCTTTTTTTT TTTTTGAGACGGAGTTTTGCTCTTGTTACCCAGGCCAGAGTCCAATGGCGCAATCTTGGC TCACAGCAACCTCTACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCATCAAGTTCCCA AGTAGCTGGGATTATAGGCATGTGCCACCACCCCTGGCTAATTTTGTATTTTTAGTAGAG GCAGGGTTTCTCCATGTTGGTCAGGCTGGTGTCGAGCTCCTGACCTCAGGTGATCCACCC GCCTCGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCGCCCGGCCACAAGCT GGCTCTTTAAAAAAGAATTAGACGGCCGGGCACGGTGGCTCATGCTTGTAATCCCAGTAC TTTGGGGGCTGAGGCGGGTGGATCACCTGAAGTCAGGAGTTCAAGACCAGCCTGGCCAAC ATGGTGGAACCCTGTCTCTACTAAAAAAACAAAATGCAAAATTAGCTGGGCATAGTGGCA TGCGCCTGTAATCCTAGCTACTCGGGAGGCTGAAGCAGGAGAATCACTGGAACCCAGGAG GCAGAGGTTGCAGTGAGCTGAGATAGTGCCATTGCACTCCAGCCTGGGCAACGAGTGAAA CTCCGTCTCAGGGAATAAAAAAAAAGAGAGAGAAACAGCTCAGCAAGCTAAGAATAGGCT GGTTCTTTATGTGCCAGGCACTATACTAAGTGTTTTCTGTGGGTTTTCTCATATAGGCCT CATCTGTGAGAGGTGTTTCTGTTATGCTTATAATTGAGGAAACAGTCCTAGAGAAATTAG GCACCCCATCCACAGTCAGATAGTCATATAGCCAGCATGGAGACGAGGCTCTGAGCTCCA GCCACTGTCCTGTCATGTTCTCTGCAGAACCACATCCCTGTGTTTAGTCCCGCACTTACA GACGGCTCGCTGGGCGACATGATCTTCTTCCATTCCTACAAGAACCCGGGCCTGGTCCTG GACATCGTTGAGGGTGAGGCGCTAGGGCCACAGAGGAGAGGGGAAGGAGGGCTGGCTGAG TCCAAGGCCTGACTTCGGCGCTCTTCCCCCAGACCTGAGGCTCATCAACACACAGGCCAT CTTTGCCAAGTGCACTGGGATGATCATTCTGGGCGGGGGCGTGGTCAAGCACCACATTGC CAATGCCAACCTCATGGTGAGTGGGGGTGGCGCTTCGGCCCACTCTGCAGACATGCTGTG TGGTGGGCCTATGCCATGTGCTGGGTAGACAGCATGAACTAGACAGGCCAGGATCCCTGC TCCCCGGGACTGATGTTCTAGTAGGGGAGATAGCAAACAAGTGACATCCACGTCAGGGGG CAGTCATTGCTACGGGGAATACTAAATGATGGCATGAGAAGAGAAAGGGGTGCTGTCCAA CAAGAGGTTTTGGAAGGAGGCTTCTGGAAGTGTGAGCTGGGAGCAGGGGTTTGGGGAGGC ATCTCCCAGGAGCTATGTGGTTGTCTCCCGTGCCAGGAGTTTGTGCTGCTGTACTAGCAT TGAGCTTCTGGATTGCAAAGTTCCCAGGAGAGGGAACAGCCATTGCAAAGGCTCTGGGGC GCCTGAAGTAATCCAGGAACAGCTGGGTACCTGGTGAGGGGAAGGTGGAGTGGTGAGGGC CAGGAGGTGATGCAGGGAGGTGCCACAGGGAGCCTGCTGGGCCCTGTGGGCTGAGGCGGG GCTTTGGCTTTTGCACTGAGAGAAGTGGGAGAGGACTTGACTCGGGTTCCCATGCTCCCC CTGGTGGCCATGTGGTGAACAGATGGTGGCAGGTGAGTGAGAACTCCAGTCCAGGACAGT GGTGACCATGCAGGGATCAGGAGGCAGGCGGTGGTTGGATTTGGAGGGCTTCTGAAGATA GAGTTGCTGGCAGCTCCTGCCTTGCAGATGGGGCAGGGTTGTTGACACCTGGCTGTTGGG TCTGGGGAAACACAGCCATCGTTGCCCAGCAGCTCTAGTGACCCCAGACATTGACATGGG CCCTGTCTGGGAGCGAATGTCTGTGAAGGGCTTCCTTCATCTGGGACACACCTCTCAGCC TGTTTGGCTACGGTGTCCTCCCTCTGTGTCTGTCTCCTGTGACTGGCTGACTGGGCCCAC CGTGCCCCCGCCTCCCCACAGCGGAACGGGGCCGACTACGCTGTTTACATCAACACAGCC CAGGAGTTTGATGGCTCTGACTCAGGTGCCCGACCAGACGAGGCTGTCTCCTGGGGCAAG ATCCGGGTGGATGCACAGCCCGTCAAGGTAAGCGCTGGCTGGGTGGGGCATAGGGTCTCT GGGACGATGAGTGTGGGTCCCATGGCTTACCCAGGTTCCCCCCTACCCAGGTCTATGCTG ACGCCTCCCTGGTCTTCCCCCTGCTTGTGGCTGAAACCTTTGCCCAGAAGATGGATGCCT TCATGCATGAGAAGAACGAGGACTGAGCGGCTGCGGTCCCAGGAAGGTCTTACCCCCTCT TCTATTTATTAATTTGCAGACCCAGCCCCTCCCCTACTTTTTGGTCAGCTACGTCTCTAG AATAAGATGGTATCTGAAGTCCTT OMIM ID 600944