Entrez gene ID | | 17250 |
Official gene symbol | | Abcc1 |
Full name | | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
Aliases | | Abcc1a,Abcc1b,MRP,Mdrap,Mrp1 |
Gene summary | | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16 A1 |
Gene position | | 14361653 - 14474968 Map Viewer |
Gene orientation | | plus |
Gene size | | 113316 bp |
Gene sequence |
| |
|