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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Mrvi1 (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID17540
Official gene symbolMrvi1
Full nameMRV integration site 1
AliasesBB115629,Irag,Ris1
Gene summaryThis gene is a putative tumor suppressor gene that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during myeloid differentiation. Studies in mouse suggest that MRV integration at this locus induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional isoforms may arise through the use of alternative non-AUG (CUG) translation initiation site. [provided by RefSeq]
LocationChromosome: 7   Locus: 7 F1|7 51.52 cM
Gene position118125609 - 118011781  Map Viewer
Gene orientationminus
Gene size113829 bp
Gene sequence