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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DNASE2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1777 Official gene symbol DNASE2 Full name deoxyribonuclease II, lysosomal Aliases ,DNASE2A,DNL,DNL2, Gene summary This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.2 Gene position 12992335 - 12986025  Map Viewer Gene orientation minus Gene size 6311 bp Gene sequence >DNASE2:complement(4248827..4255137):Length=6311 GAGTCTGTACCCTCGTGATGTCCCCGCCCCGGTTCCCAGGCAAGTTTAGGGAAGTGAAAG GCGCCAGGTGCCAGTCCTGGCCTCTGATGTAACCCAGCGCCCCGCAGTCCCGACACAGAT TCCTGGATCTCAGCCCCATAGCAGCTATGATCCCGCTGCTGCTGGCAGCGCTGCTGTGCG TCCCCGCCGGGGCCCTGACCTGCTACGGGGACTCCGGGCAGCCTGTAGACTGGTGAGTGC GCAGCGGGGGGCCTACCATCGCCCCGGGGTCCGGCTGCGGTCACTCAACCGGGATGGCTA CCTCCTCGGGGAACCCTGGGGTGCCTTCTCTTCCCTCTCTCCTATTTCTGTGCATTCTCC GACCTCCAGGTTCGTGGTCTACAAGCTGCCAGCTCTTAGAGGGTCCGGGGAGGCGGCGCA GAGAGGGCTGCAGTACAAGTATCTGGACGAGAGCTCCGGAGGCTGGCGGGACGGCAGGGC ACTCATCAACAGCCCGGAGGGGGCCGTGGGCCGAAGCCTGCAGCCGCTGTACCGGAGCAA CACCAGCCAGGTGAAGGGGGCCCCGGGCCAACTAGGGGCGAAACTCTAGGGCTGCCCTGC CTGGGAGGAATTTCACGTTGCCTCCGTTTATCCGCCCGCAGCTCGCCTTCCTGCTCTACA ATGACCAACCGCCTCAACCCAGCAAGGCTCAGGACTCTTCCATGCGTGGGCACACGAAGG GTGAGGCCTGGATTGGGGGCTGGGGAGAGACTCGGGTCCCATTTTTCCAAGGTAACCCCT GACGTGCATGGGGTGGTCGGGGAGATCTGCACTGTCAGACCCTGGGCATCTATTCCCCCC AACTTTTTTTTTTCTTTGTTTTTGAGACGGTGGGAGTTCGCTCTGTCACCCAAGCTGGAG TGCAGTGGCACAATCTTGGCTCACTGCAATCTCTGCCTCTGGGGTTGAAGCAATTCTCCT GTCTCAGCCTCCCAAGTAGCTGGTATTAAAGGCGCACCATCACACCAGGCTAATTTTCAT ATTTTTAGTACAGACGAGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGTTTC TACCTCAAGTGATCTACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGAATGAGCCA CCCTGCCCAGCCGAGTTCCTATGCATTTTTCCAAGCTAACCCCTGACCTCCATAGTGGGG TGGGAGATCTCCCCTGTCAGACCTTGGGCATCTATTTCCCCTATTTTATTTTCTTTTAGA CAAGGTCTCACCCAGTCACCTAGGCTGGAGTGCAGTATCACAGCTCACTGCAGCCTTGAC CTCCCAGGGCTCAGGTGATCCTCCTACCTCAGCCTCCCAAGTACTGGGCCTGCCGGTACC CCCCACCACGCCTGGCTTTTTTTTTTTTTTTTTTTTTTTGCGGCACTCTCTCTCCATCAC CCAGGCTGGAGTTCGGTGGTGCAATCTCAGCTCACTGCAATCTCCATCTCCCCAGTTCAA GCGATTCTTCTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGTGTGCGCCACCATGCCC AGCTAAATGTTGTATGTTTTAGTAGAGATGGGGTTTTACCAGGTTGGACAGGCTGATATT GAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGC GTGAGCCACCACACCTGGCCTACTTTTTGTATTTTTGTAGAGTGGGCTTTTGCCATGTTG CCTAGGCTGGTCTCTAAGTCCTGGTTCAAGCAATCCACCCACCTTGGCCTCTTAATGTGC TGCGATTACCGGCATGAGCCGCCACACCTGGCCTGTTTCCCTACCTTACATTACTCTTGG CGTTATTCTGGACTATAAGAATTTATGCCTGCAAAAACTGAGCTCAGCTGTGGTTCTAAC ACTGCTGGCACCCTCTCTAAGCCCCGCTGCAAACTGAGGGTGTTCCTGATTGCAGATGAG CTTGCTGGGAGGCCTGGAGCAATACCCTCTAATTGCCTTTTTTTTTTTTTTTTTTTTGAG AAGGAGTTTTGCTCTTGCTACCCAGGCTGGAGTGCAATGGTGCAATCTCGGCTCACTGCA ACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGATTA CAGGCATGCACCACCATGCCCGGCTAATGTTGTATTTTTAGTAGTGATGAGGTTTCTCCA TGTTGGCCAGGCTGGTCTTGAACTCCCGACCTCAGGTGATCCGCCCTCCTCGGCTTCCCA AAGTGCTGGGATTACACTGCGTGGGGCCTGCCTTCTTTTTTTAAATTTTTATTTATTTAT TTATTTATTTATTTATTTACTTACTTACTTACTTATGTTTGAGATGAAATTTTGCTCTGT GGCCCAGGCTGGAGTGCAGTGGTGGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTC AAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGTCCACCACCACGC TCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGCTGATTT CTAACTCCTGACCTCAGGTGATCTGTGTGTCTCGGTCTCCCAAAGTGCTGGGATTACAGG CGTGAGCCACTGCGCCCGACCTCCCCTAATGCCTTCTTTTGGTCCAGGTGTCCTGCTCCT TGACCACGATGGGGGCTTCTGGCTGGTCCACAGTGTACCTAACTTCCCTCCACCGGCCTC CTCTGCTGCATACAGCTGGCCTCATAGCGCCTGTACCTACGGGCAGACCCTGCTCTGTGT GTCTTTTCCCTTCGCTCAGTTCTCGAAGATGGGTAAGTCGAGTCAGGGACACAGGATGAG TCCTGGGTTTACTGACCAGAACCTGGAACGATCTTGCATTTCCTCCTCCCCTTGTCCTCC AGGCAAGCAGCTGACCTACACCTACCCCTGGGTCTATAACTACCAGCTGGAAGGGATCTT TGCCCAGGAATTCCCCGACTTGGAGAATGTGGTCAAGGGCCACCACGTTAGCCAAGAACC CTGGAACAGCAGCATCACACTCACATCCCAGGCCGGGGCTGTTTTCCAGAGCTTTGCCAA GTTCAGCAAATTTGGAGATGGTGAGTCTCAAGGTTGAGGGTTGGAGAGCTCCTTCTCTGC AGACAGGGTGACTGGTGTGGCCATGGCTGAGTTCAAGTCAGCGGTAGAGACCAGGTCTGT TTGGGAGCTATAATCACATGATCAGTGAACAGACCTGGGTTCAAACCCTGGGTTTTGCTG TGTGATGTATAACTTCACCTGAGCCTTGGTCTACTCATCTGAAAAATGGGGATACTGACA TCTACTTAAAAAATTGTGAATGAAGTGGTACCTGTAAGTCATTTGGGTGCCAGAGGTGGT GCCTCACTCCTGTAATCCCAGTTACTTAGGAGGCTGAGGCAGGAGGATCATTTGAAGACA GGCATCCAAGACAAGCCTGGGAAACATAGCAAGACCTCATCTCTACAAAATTAAAAATTA GCCAAGCAACTTGGGAGGCTGAGGCAGGAGGATAAATTGAGCCCAGAGTTTCAGACTGCA GTGAGCTATAATGACTCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTTTA TTTAAAAATAAATAAATAGGCTGGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGG GAGGCTGAGGTGGGCAGATCACGAGCTCAGGAGATCGAGACCATCCTGGCTAACACGGTG AAACCCTGTCTCTACTAAAAGTGCAAAAATTAGCCAGGCATGGTGGCGGGCACCTGTAGT CCCAGTTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGAAGGTGGAGCTTGCA GTGAGTCAAGATAGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTGTGTCTCAA AATAAATAAATAAATAAATAAATACAAATAAATAGGCCAGGCACAGTGGCTCACACCTGT AATCCCAGTCGAGGCAGGAGGATTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAAC ACAGCGGGACCCCATCTCTACAAAAAAAATTTTAATTAGTGGGGCATAGTGGCACACACG TGTAGTCCCCACTACTCAGGAGGCTGAGGTGGGAGAACAGCTTGAGCCCAGGAGGTCGAG GCTGCAAGTGAGTCATGATCCTGCCACTGCACTCCAGCTGGGGTGTCAAAATGAGACCCA GTCTCAAAATAAATAAGTTAATTAATTAAAAACACTCAGGGCCGGACGCGGTGGCTCACC TGTAATCCCCACATTTTGGGAGACCAAGGCGGGTGGGTCACTTGAGCCCAGGAGTTCAAG ACCAGTCTGGCCAACATGGTGAAACTCCATCTCTACTAAAAGTACAAAAATTATCTGGGC ATGGTGGAGGGCGCTGGCTGATTACACGGTCAGGAGTTTGAGAACAGCCTGGCCAACATG GTGGAACCCCATCTCTACTAAAAGTACAAAAATTAGCCGGGTGTGGTGGCGGGCACCTGT AATCCCAGCTACTCAGGAGGCTGAGGCATGAGAATCGCTTGAAACCAGGAGGCAGAGGTT GCAGTGTGCCGAGATTACACCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCTGTCT CAAAAACAAATTTGGGAAGGGCAATTAATATTAATGTCATCATTCCCAGGACTGGGAATT GACAACTGAGCTCAGAAATATGGAAACTGTGGCAGGGCGCGGTGACACACACCTGTAGTC CCAGCATTTTGGAAGACCGAGGTGGGCGGATTGCTTGAGATCAGGAGTTTGAGACCAGCC TGGTCAATATGGTGAAACCCCTCTTTATTAAAAAATTAGCCGGGTATGGTTGTGCATGCC TGTAGTCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCACTTGAACCTCGGAGGCAGAG GTTGCAATGAGCCTAGATTGCACCAATGCACTCTAGCCTGGGCGACAGAGCAAGACTCCA TGTCAAAAAAAAAAAAAAAAAAGGAAATATGGAAACTGAGCTGAGAGAGGGGAAGTGGAC TAGGGACTCCCTCGCAGTGGCCCTGACCCTACCTGTGCCCTCTCTCCATCCTTTGCAGAC CTGTACTCCGGCTGGTTGGCAGCAGCCCTTGGTACCAACCTGCAGGTCCAGTTCTGGCAC AAAACTGTAGGCATCCTGCCCTCTAACTGCTCGGATATCTGGCAGGTTCTGAATGTGAAC CAGATAGCTTTCCCTGGACCAGCCGGCCCAAGCTTCAACAGCACAGAGGACCACTCCAAA TGGTGCGTGTCCCCAAAAGGGCCCTGGACCTGCGTGGGTGACATGAATCGGAACCAGGGA GAGGAGCAACGGGGTGGGGGCACACTGTGTGCCCAGCTGCCAGCCCTCTGGAAAGCCTTC CAGCCGCTGGTGAAGAACTACCAGCCCTGTAATGGCATGGCCAGGAAGCCCAGCAGAGCT TATAAGATCTAACCCTTATGGCCAGGTGCAGTGGCTCACGTATGTAATCCCAGCACTTTG GGAAGCCAAGGAGGGAGGATCACTTGAACTCAGGAATTCGAGACCAGCCTGGGCTACATA GTGAGACCACATCTCTACTAGAACTTAAAAAAAGTTAGCCAGGCACGGTGATAAATGCCT GTAGTCCCAGCCACTGAAGCCAGAGGATCGATTGAACCAGGGAGATCATGGTCACAGTGA ACTATGATTACGCCAACCTGGGTCACATAGCAAGACTCTGTTTCAAAAAAAAAGGGGGGG CGGGGGACGGGTGGGTGCAGTGGCTCACATCTGTAACCCCAGCACTTTGGGAGGCTGAGA TGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCA TATCCATTAAAAATATTTAAAAATTAGCCAGACATGGTGGCACGCGTCTGTGGTCCTAGC TCCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACTCGGGAGGCAGAGGTTGTCATGAGC TGAGCTAACACCACGGCACTTCAGCCTGGGTGACAGAATGAGACTCTGTGTCAAAAAAAT AAAAAATAAAAAATCTAAGGGCTCAGGAACCAGTTTGGACTTGATTTTGAATCCCAGTTC ATCCCCTTCCTAGCTGTATGACCTTGATTGTGTGCCTTAACCGCTCTGTGACACAGTCTA CCTGTCTGCAAAATGGGAAACATAATACCTGCCATCAGGATTGTTGAGGAGTAAATAAAT GGAAATTGGTG OMIM ID 126350