Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DNM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1785
Official gene symbolDNM2
Full namedynamin 2
Aliases,CMT2M,CMTDI1,CMTDIB,DI-CMTB,DYN2,DYNII,
Gene summaryDynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.2
Gene position10828729 - 10942586  Map Viewer
Gene orientationplus
Gene size113858 bp
Gene sequence
OMIM ID602378