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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Mx2 (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID17858
Official gene symbolMx2
Full namemyxovirus (influenza virus) resistance 2
AliasesAI528743,Mx-2
Gene summaryThis gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to vesicular stomatitis virus, a member of the rhabdovirus family, but not to influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a frameshift that inactivates this gene product. [provided by RefSeq]
LocationChromosome: 16   Locus: 16 C4|16 71.2 cM
Gene position97757688 - 97782508  Map Viewer
Gene orientationplus
Gene size24821 bp
Gene sequence