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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DNMT3A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1788
Official gene symbolDNMT3A
Full nameDNA (cytosine-5-)-methyltransferase 3 alpha
Aliases,DNMT3A2,M.HsaIIIA,
Gene summaryCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p23
Gene position25565459 - 25455845  Map Viewer
Gene orientationminus
Gene size109615 bp
Gene sequence
OMIM ID602769