| Entrez gene ID | | 18245 |
|
| Official gene symbol | | Oaz1 |
|
| Full name | | ornithine decarboxylase antizyme 1 |
|
| Aliases | | AZ-1,AZ1,Antizyme,ODC-Az,Oaz |
|
| Gene summary | | Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation. [provided by RefSeq] |
|
| Location | | Chromosome: 10 Locus: 10 C1|10 43.0 cM |
|
| Gene position | | 80289401 - 80292035 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 2635 bp |
|
| Gene sequence |
| |
|
