Entrez gene ID | | 1838 |
Official gene symbol | | DTNB |
Full name | | dystrobrevin, beta |
Aliases | | ,MGC17163,MGC57126, |
Gene summary | | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p24 |
Gene position | | 25896503 - 25600112 Map Viewer |
Gene orientation | | minus |
Gene size | | 296392 bp |
Gene sequence |
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OMIM ID | | 602415 |
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