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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DUSP7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1849 Official gene symbol DUSP7 Full name dual specificity phosphatase 7 Aliases ,DKFZp586F2224,MKPX,PYST2, Gene summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM] Location Chromosome: 3   Locus: 3p21 Gene position 52090461 - 52082935  Map Viewer Gene orientation minus Gene size 7527 bp Gene sequence >DUSP7:complement(52022935..52030461):Length=7527 GCGGCTGGGGCCCGCGCGGCCGGGGCGCCGTCCCAGGGCAGGGCTGCCCGGCCCCGGCCC CGGGCCGCCCGCGCTCCCCATGAAAAACCAGCTCCGCGGCCCCCCAGCGCGGGCGCACAT GTCGACTTCGGGGGCGGCGGCGGCTGGGGGCACCCGGGCGGGGTCCGAGCCCGGTGCGGG GTCGGGGTCCGGCGCAGGCACCGGGGCGGGCGCGGCGACGGGGGCAGGGGCCATGCCCTG CAAGAGCGCCGAGTGGCTGCAGGAGGAGCTGGAGGCGCGCGGCGGCGCGTCCTTGCTGCT GCTCGACTGCCGGCCGCACGAGCTCTTCGAGTCGTCGCACATCGAGACGGCCATCAACCT GGCCATCCCGGGCCTCATGTTGCGCCGCCTGCGCAAGGGCAACCTGCCCATCCGCTCCAT CATCCCCAACCACGCCGACAAGGAGCGCTTCGCCACGCGCTGCAAGGCGGCCACCGTGCT GCTCTACGACGAGGCCACGGCCGAGTGGCAGCCCGAGCCCGGCGCTCCCGCCTCCGTGCT CGGCCTGCTCCTACAGAAGCTGCGCGACGACGGCTGCCAGGCCTACTACCTCCAAGGTGA GGGCGGCACCGAGACGCCTTACGGGATCGGGGCCCCCCCGCGACTCCCTGACGCCCCCCT TGGAGGCGCTTTCCTCTCCACGCGCTCGGCCTGCCCCTCTGGGCGCCACGTCGTCCCCGG CCCGCATCCGCCCTCCTGGAGCCGGGTCCCCACTGTGTGGTTTGGCAGGCGCGGGGCTCC CTCTGCGCCCCCTTTCTCGGCACGATTCGAGTGGGTGGAACAAACTTTCCCCTGCCTGGG GTTTCCTTTTTTTTCCTGTTGATGGGGCGACAGTAGTGCCTGGGCTCCAGTGGAGCCCCT CAGAGGTGGAAGGCGCCGCCTCCCAGAACCCTAAAAGCGGCAGGGCGCCCAAGTCCAGCC TAGAATTCGTGTTTCTGGAAGGCCAGGATCAGGAAGGGCACCTTTCATAGCACCATCCTC ACCTCCAGCGCATGGAGACCATTTGGGTTGGGGTCTCCTGGATCCGGGAATTGCTTCTTC CACCGGAGAATTGCCGCCTCTAGGAGGCGCTTGGGGCAGGGTATGGGCAGGCTCCATTGC CCTGGCCCGGGTCTCTCGGGACCCCCAGGTCCCTAGCCTGCTGCCCCGGAGCTTGCAGAA GGGAGAGGTAGCACCGGGGGGCGAGTGGCTGAGGCCGGTGTTTCCAATTAACATTCCAAA ATGGCCTCTTGCTGGCAGCGGGGCGGGCGGGAGGGGAGGGGAGGCCTGCGGCACCCTCGG GCGCAGGGCCCATGCCTCGCTGCAAGGGGCTCCCCATTTCTCCTGTCCCTGTATCGCCCC AGTGGCCCTCCCCCGCTGCAGGTCCAAGGCTGGGGGTGGGGCTTGTGTTCTAAGGGAGGG TTCTAGAGAAGTGGAGCCAGGACCCCCTTCAAAAACCTGCCCCTGCTGGGGGAAGGGGCC AGCCAGTACCTTCCCACTACCCTCCCCAGCTGTAGTTTCGGGGCTGGGCAACCACTAGAC TCCCGTTCAGGAAGCCCAGGACCTCTCTGCCTCTAACTGAGCCAGATGTGGCTCTGGCAC CTGTGGTCTCATCTATAAGAGGAGTTTGCCAACCCAGAGGTGCTGGCTAAGATGGGGTTG TCTGCTTTTCTTTACCACTTAGCTGTTACTGAACACCCATGGGTGCTAGGTGTGCGTGGG AGCTGCAGAAGAGGAATTAGCTGGGGCCTGTCCTCAAGTGCCCTAAAGCTGGTGCCATGG CTGGGGGCCCCGAAGTGTTATGGGTACCAGTTTGGAGTCCAGGCACGTCACTTCACCTTC TGGGGCCTCAGTTTCCTTATCTGTGAAGTGGTCATGGTTTAGATGGAGAGAACACGAGAG AGGGCACACGTGTAACATGCTTGGCATGGCCCATGCTGACCGTGGGTGCTGTGGTGTTTG GCGTGCAGAGTCCTGGCCATCTCTGGTCTTGTGCAGCCCATCTGGGCTCTCACCAGCCTC TCACCCAGGCCCTGTCTCACCCTGGACACAGGTGGTTTCAACAAGTTTCAAACAGAGTAC TCTGAGCACTGCGAGACCAACGTGGACAGCTCTTCCTCGCCGAGCAGCTCGCCACCCACC TCAGTGCTGGGCCTGGGGGGCCTGCGCATCAGCTCTGACTGCTCCGACGGCGAGTCGGAC CGAGAGCTGCCCAGCAGTGCCACCGAGTCAGACGGCAGCCCTGTGCCATCCAGCCAACCA GCCTTCCCTGTCCAGATCCTGCCCTACCTCTACCTCGGCTGCGCCAAGGACTCCACCAAC CTGGACGTGCTCGGCAAGTATGGCATCAAGTATATCCTCAATGTCACACCCAACCTACCC AACGCCTTCGAGCACGGCGGCGAGTTCACCTACAAGCAGATCCCCATCTCTGACCACTGG AGCCAGAACCTCTCCCAGTTCTTCCCTGAGGCCATCAGCTTCATTGGTAGGTGCTGTGTG CTGGGCAGGGGGGTGTGGGTGCATCAAGGTGTATGCAGGACTCTGGGTGGCGCCCCCGCC TGACTGGGTACCTCTGGGCCTGTTGAGACCTGTGTGTGCCCTACGTGTGCCAGCGTGTGC CCGTGGGTGTACCCAGGCCTACTGTGAGTCACCGAGTCCCTTGGGCCCCTCTACCTGTTG GGGCCTGAGCAGTCTCCTGAGTCCTGAGCTCCCCCTAGCTGACAGCACGTCATGGGCTCT CTGCTGTCCAGCTTGTGTTTTCCTGGCTTAGATGTTGTTTCGGGCTTAGCAAGCTGAAAC ATCACAGCGCACAGACCTCCCACGGGTCTCACTTGCTCCGCATCACGCCTCAGCACACGT GTCTCTCCAGGATGGGGTTGTCATAGTGCCTCTTTGGGCTTTAATGTGGACCTAAGAGGG CTGAAAGGTAGCCCTGGAGCCAGAGGCACACCCCAAACAGGCAGCTATTGAAATGTGGTG ACTGCTAGCTCAGTCAGCCTCCAGATGCTCTCTGCAGCCTGTAGGGCTTGCTTGGAGTGT AGGGAGGAGTGCAAGAGAAGGTGGGGGAGTGGAGAAAGGCCTTCCCCAGAGCAGTGTGTC CTGCTGTCTGGCTTAGTGCCCTTCGAGTCCCTGTATCCCCAGCCTCAGCAGACTCGGGTC CCCACTGCTTTCTCCTTGGCCAGCTGGAGGCTGAGACCACAGGTCATCTCCCCTGGCCCA GGGTGCAAGGAAGGGGCACGAGGGCTCAGGATGAATGTAAACGCTCTATCTCTGAGCCTG GTGACCCAATGTTTCTGCCCAGCCTCCAGTGGCAAGGTGTGGGGGTGGCCCGGGCTGTCT TTTCCCGATGGTGGCTGTGTCCAGTGGAGGGCGTTTTGGTGTCGGCTGGGCTGGGCTAGC TTTAACAACAGGAAGTGGGAGGCTTCCCCGCCTCATCCGCTTACTGGGAACCAAAAGTAG GTGCCTGGCTGGGAGGAAGGAAGGAAGCTGAGGCCTGGGGGAGGGGCTGCAACTGGGGCT GCCTGGAGCTTCTCAGCCCTGCCCACCACCCCCTGGGTCAAGAGGGCTAGGGGTGCTGCC TCAGCATTTGAACTCCCCCAACGAGGGAGGGGAATAGAGAGAGGGAAGCAGGCTTCGCCA GGCTGGGCCTGGCTAGTGGGTACCTTTATCCTTCCTGAAAGCTCCTCCCCGTCTGGGTAG GGGGACCTTTTTCCTCATTTGACAAGTGAAGGAATTGAGGCCCAGGCATCCCTTAGGAGT CAGTGGGACAGGATCAGTCACCAGCTACACCCTGAAAAGGCCAAAAATAAAGCCAGCAGA AACAGACTGTCTTTGGATCACCTGGAGGTGGGTTTGGAGGCCAGGCGTTCCTCACATCCT GGTGTCACCACTGGAGGCTGGTCCCAGCACCCCCTTTTCCCACCCCCAATCTCGAGGTCT GACCACACAGCTCCTCATGAAGCTGCAATGTCTGTCTCCTTGCCAGATGATCCTGCCCCA GTGCCTTAGCCATGGGGCCCCCTGTCAGTCCCTGAGTCTGGAGGAAGCACCTACTGTATG CTTTACTCCTTGGTTGGGAGGGGATGGGAGAGGAAGCTCTGTCAGGACAAAGGCAACGAA GAACAGTGGGTGAACCCGTATGTCATCTTGTAGGAAGGCATTGATTGCGTGCTAGCTGTG TGCCTGGCTCCTGGAGGGTTCAGAGTCAGGGTGGTGGGGACATCAAGGACCCCATGGCTG CCTCTTGTGAATCTATGTCCCTGGCACAGCTGTGGCACACAGAGAGGCAGCTGCCCCGGG GTCCAGGAGAGATTACAGGACTGAGTTGTTCAGTAGCTCGGCCAGTATTTATTGAGCTTC TATGTGTCAGACAGAGGAGTCTGAGGGTGGCACTGGGGGAAGCTGGGAGGGTTGGAGGGG AAAGGGGACAGGAAGGTTGGCCCCATCCAGTCAGCTGTGGTAGGAGATATCACTGACACA TGGGCCTCCTGAGGAAGGTCTAGCAAGTGGCAGGGGTGGGGCCCATTTAAGCACACCTCA CTTATGAAGCCCCATCACAAGTGATAGTGTGGCCATCATCCCAGTCCATGTGTCTTAGGA GCTGGAGTTAAGGCCTTGGGGACTAGCTGGGCAGATGGCAGAGCGAAATGCAGGGCCAGG CCACCTACTTCCTTCCAGAGGAGCCTCCCTCAGGCCACTTTCCTAGAAGACTCTCAGGGA CAACCCATGGGAGCGGCTCCAAGAGAACCAGCCCAGCCCCCAGTCCCAGGTCATGGCCTG GCAGCAGCGGGCGCTGAGCTAGGAGGAGCTTCTGTGTGGCCTTGGGCTTGCCACTTTGTC TCTGTGTCTGTTTCCTCGTTGATAAAATGGGCTTACTGGCCATGGTGCAGATGACCCAAG AGGATGCAGGTGACACCCGTGACAGCAGTCGTTAACGCACATGGCAGTGGTAGGACTAGC CATGATCACAGGCATTACAGTAGTTCATGTTTGTTGACCCCTCACTTGGCTCAGGTCCTT ATGAGACCACTGTGCATAAATAGGCCCATTTTATAGATGAGGAAACAGACACGGGTGTCC AGTGCCTTGGGGCTAAAGTGTGCAGAGCCCTCTCCACAGCAGTGCTGTTGACCTCTATTC CAAGTTGCTGCCCTACCCACACTGGGCTTGGCCAGGTCCCTCAGGGGTCGGGCAAGACCA GCCAGCCACCATGCTGCCCTCTGTGCCCCAGCCCCACCTGCCCACCCATGTGGGAAGGCT CCTTGAAGGAGGCACCTCCCTGACCCATGCCAATGTGTTTCAGACGAAGCCCGCTCCAAG AAGTGTGGTGTCCTGGTGCACTGCCTGGCAGGCATCAGCCGCTCAGTGACGGTCACTGTG GCCTATCTGATGCAGAAGATGAACCTGTCACTCAACGACGCCTACGACTTTGTCAAGAGG AAAAAGTCCAACATCTCGCCCAACTTCAACTTCATGGGGCAGCTGCTGGACTTTGAGCGG ACGCTGGGGCTAAGCAGCCCGTGCGACAACCACGCGTCGAGTGAGCAGCTCTACTTTTCC ACGCCCACCAACCACAACCTGTTCCCACTCAATACGCTGGAGTCCACGTGAGGCCTGGTG CACGGGGGGCATGGCACCAGGCCCCTGCTCGGCTCTCCACAGGGCTAGGTGGGAGAGCCC AAGCCCGCCACCTCTGGCCTGAGGAACCCCCAGATGTCACCTGTGCCCAGAGGCCCAGGC TGATCGGTGTCGGAGCGCCCCTCACCATCCTTGGGGGCAGGGCCCGCAGGCAAGGTCTCC CACTGCAGGGCTTGCTGGAGAGGCCTCGGCTCTTGGACACGTGGCTTTGGGCGTCCACCA GGGCCTCATCCTGTCCAGGACGCTCCTTTCTGCTGACAGCCCAGCCAGTTTGGCTGTTTT TTAAAGACACATCCACGGACCTGAGTTTACTTTTTACTTTTGGCAGGTAAATCCAAGCTC CCTGGAGCACAAAGAGTGTTTGAGCTCTTCTTGATTTTTCTTTTTTTTTTTTTTTTTTAA CAAAAAGTGTTATTTTCAGGCTACATGCAACAGTGGATTGTATAACCCAGTATTTCATCC CTTTCCTGATCCTGCAAGAGAGAGAAATGTTCAGTTTTGTTTTTCGTTCAATTTCAAAAA GCAAGTATCGTGTTTGTTTTTGTTTTTGTTTTTTAATGGAAAAGACAGACGCCATGTTGA CCTTGACCAAATGCGTTTTGCACATGTGTGAAGCCTCTGTTTCCTCAGCGGGCCCTTCTT GAAGGGGTGGCTTACTGCTCTTCAGGTATTGGGACCCCCAGTCGTGCCGCCTCCCACCCT TGGCCCAGTCTGACTTAGCTCTGCATTCGCCTGTGATGACTGCTGCAAGTTGTGATTGGT GGGCTGGATGGTGGTCTTTGCATTTTCTGCCGTCTCATCCATCCCTCTGGTGGTCCCTGC AGACCTCCCTGAGGCAGAAGGTGGGGACCCTGGGGCCCTGCCGCTGTCCCCCAGGAGGTG GGCCGCAGGGGGCTGCCAGGCAGTAGCATTAGCCCTCTGGGGTCAGCCCCTAAGAAGGCC TGGGCTCTGAGCCCTTTTATATACTTAGCCACTACTTCTGTCTGTCTGTCTGTCTCTCTC TCTTCCTCTCCCTCTCTCTCTTTCTCTCTCTCCCTCTCTCTCTCTTTCTTTCTCTCTCCC CCCCTCCCTCTCTCTTCCTTTCCTCTCTCTTGTTGTAACTGGGAGTGGAGGCCCAGTGGC TGGGGAGACATTAGGTGGTGGGGCCCAGCCCGACCTCCAGGTTCTTCCTTCTCCCTAGCT GTTGCTTTGGTCTGGCCACTCCCAGCCCCCTTGTCCCCTTGGAAGCTTGCCCTGCCCTCA TCTTGCCCATGCCTTCTACTGCCAGGAGACTTGCACCCATTTCAACCCTAGGGCGGGGGC AAGTGGGGCAAGGATGGACCAGCAGAAGGGGGGTAAGGCTCTGTTCACTTCCCCCTGCCT CCACAGAACGAAGCCACGGATTCCGTTATCTTCCTCCAGTTTTGTTCCTTCTCCAGCCTC AGTTCCACCAGGTGTCAGGACTGCATGGGGGCCTGGGGCAGGCAGAGGAGTCAGGCCAGG GTCCCTGACGGAGCAGCACTCAGCATGTGAGTGAGGCCACAGAAAAACTCTGCCCCACTG CTTCTTACCTCACGGGGGTGGCTTTCAGGGATTCTTTAGCGCAGCAGATTAAAATCTTGC CACAGTCGAGAAATTGACAACAAGCTTCCATGCTGTACATGGTTCTCTTTTTCTCTCTTT TATTTTTAAAAAGAAAACCCAGAAAGATGTACCAGATTTGTGTAAATGAGGGTATGCCAG AAGGTGGCCAGTTTTGCTTTATGATCTTATGAAGGAAGATTTGTGACCCTACGTATATAT ATACACACACATACATATATATATATATCCCGAACCAACAACGGGACTTTGTTTATATTG CAAATAAATATTATTTTTTCTTTAAAA OMIM ID 602749