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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AGTR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID185
Official gene symbolAGTR1
Full nameangiotensin II receptor, type 1
Aliases,AG2S,AGTR1A,AGTR1B,AT1,AT1B,AT1R,AT2R1,AT2R1A,AT2R1B,HAT1R,
Gene summaryAngiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q21-q25
Gene position148415658 - 148460790  Map Viewer
Gene orientationplus
Gene size45133 bp
Gene sequence
OMIM ID106165