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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DUSP9 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1852
Official gene symbolDUSP9
Full namedual specificity phosphatase 9
Aliases,MKP-4,MKP4,
Gene summaryThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq]
LocationChromosome: X   Locus: Xq28
Gene position152907897 - 152916781  Map Viewer
Gene orientationplus
Gene size8885 bp
Gene sequence
OMIM ID300134