Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for APLNR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID187
Official gene symbolAPLNR
Full nameapelin receptor
Aliases,AGTRL1,APJ,APJR,FLJ90771,FLJ96609,HG11,MGC45246,
Gene summaryThis gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q12
Gene position57004927 - 57001051  Map Viewer
Gene orientationminus
Gene size3877 bp
Gene sequence
OMIM ID600052