Entrez gene ID | | 1909 |
Official gene symbol | | EDNRA |
Full name | | endothelin receptor type A |
Aliases | | ,ETA,ETAR,ETRA, |
Gene summary | | This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q31.22 |
Gene position | | 148402069 - 148466106 Map Viewer |
Gene orientation | | plus |
Gene size | | 64038 bp |
Gene sequence |
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OMIM ID | | 131243 |
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