Entrez gene ID | | 192897 |
Official gene symbol | | Itgb4 |
Full name | | integrin beta 4 |
Aliases | | AA407042,C230078O20,CD104 |
Gene summary | | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11 E2|11 76.0 cM |
Gene position | | 115836039 - 115869725 Map Viewer |
Gene orientation | | plus |
Gene size | | 33687 bp |
Gene sequence |
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