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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Itgb4 (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID192897
Official gene symbolItgb4
Full nameintegrin beta 4
AliasesAA407042,C230078O20,CD104
Gene summaryIntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11 E2|11 76.0 cM
Gene position115836039 - 115869725  Map Viewer
Gene orientationplus
Gene size33687 bp
Gene sequence