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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EIF2D (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1939
Official gene symbolEIF2D
Full nameligatin
Aliases,HCA56,LGTN,
Gene summaryThis gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q31-q32
Gene position206785904 - 206764974  Map Viewer
Gene orientationminus
Gene size20931 bp
Gene sequence
OMIM ID151625