Entrez gene ID | | 1942 |
Official gene symbol | | EFNA1 |
Full name | | ephrin-A1 |
Aliases | | ,B61,ECKLG,EFL1,EPLG1,LERK1,TNFAIP4, |
Gene summary | | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q21-q22 |
Gene position | | 155100349 - 155107386 Map Viewer |
Gene orientation | | plus |
Gene size | | 7038 bp |
Gene sequence |
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OMIM ID | | 191164 |
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