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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EFNA1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1942
Official gene symbolEFNA1
Full nameephrin-A1
Aliases,B61,ECKLG,EFL1,EPLG1,LERK1,TNFAIP4,
Gene summaryThis gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21-q22
Gene position155100349 - 155107386  Map Viewer
Gene orientationplus
Gene size7038 bp
Gene sequence
OMIM ID191164