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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EFNA5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1946
Official gene symbolEFNA5
Full nameephrin-A5
Aliases,AF1,EFL5,EPLG7,GLC1M,LERK7,RAGS,
Gene summaryEphrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q21
Gene position107006596 - 106712590  Map Viewer
Gene orientationminus
Gene size294007 bp
Gene sequence
OMIM ID601535