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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CELSR3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1951
Official gene symbolCELSR3
Full namecadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
Aliases,CDHF11,EGFL1,FMI1,HFMI1,MEGF2,RESDA1,
Gene summaryThe protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p24.1-p21.2
Gene position48700348 - 48673896  Map Viewer
Gene orientationminus
Gene size26453 bp
Gene sequence
OMIM ID604264