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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ENG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2022
Official gene symbolENG
Full nameendoglin
Aliases,CD105,END,FLJ41744,HHT1,ORW,ORW1,
Gene summaryThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q33-q34.1
Gene position130617047 - 130577291  Map Viewer
Gene orientationminus
Gene size39757 bp
Gene sequence
OMIM ID131195