Entrez gene ID | | 20289 |
Official gene symbol | | Scx |
Full name | | scleraxis |
Aliases | | BB114693,Bhlha41,Scl |
Gene summary | | This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15 D3|15 43.3 cM |
Gene position | | 76287868 - 76289898 Map Viewer |
Gene orientation | | plus |
Gene size | | 2031 bp |
Gene sequence |
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