| Entrez gene ID | | 203100 |
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| Official gene symbol | | HTRA4 |
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| Full name | | HtrA serine peptidase 4 |
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| Aliases | | ,FLJ90724, |
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| Gene summary | | This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq] |
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| Location | | Chromosome: 8 Locus: 8p11.22 |
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| Gene position | | 38831668 - 38846181 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 14514 bp |
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| Gene sequence |
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| OMIM ID | | 610700 |
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