Entrez gene ID | | 205564 |
Official gene symbol | | SENP5 |
Full name | | SUMO1/sentrin specific peptidase 5 |
Aliases | | ,DKFZp564O1016,FLJ42398,MGC27076, |
Gene summary | | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM] |
Location | | Chromosome: 3 Locus: 3q29 |
Gene position | | 196594727 - 196661585 Map Viewer |
Gene orientation | | plus |
Gene size | | 66859 bp |
Gene sequence |
| |
OMIM ID | | 612845 |