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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SENP5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID205564
Official gene symbolSENP5
Full nameSUMO1/sentrin specific peptidase 5
Aliases,DKFZp564O1016,FLJ42398,MGC27076,
Gene summaryThe reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM]
LocationChromosome: 3   Locus: 3q29
Gene position196594727 - 196661585  Map Viewer
Gene orientationplus
Gene size66859 bp
Gene sequence
OMIM ID612845