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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACSL3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2181
Official gene symbolACSL3
Full nameacyl-CoA synthetase long-chain family member 3
Aliases,ACS3,FACL3,PRO2194,
Gene summaryThe protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q34-q35
Gene position223725732 - 223808119  Map Viewer
Gene orientationplus
Gene size82388 bp
Gene sequence
OMIM ID602371