Entrez gene ID | | 2196 |
Official gene symbol | | FAT2 |
Full name | | FAT tumor suppressor homolog 2 (Drosophila) |
Aliases | | ,CDHF8,CDHR9,HFAT2,MEGF1, |
Gene summary | | This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q32-q33 |
Gene position | | 150948505 - 150883653 Map Viewer |
Gene orientation | | minus |
Gene size | | 64853 bp |
Gene sequence |
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OMIM ID | | 604269 |