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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL21 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID219927
Official gene symbolMRPL21
Full namemitochondrial ribosomal protein L21
Aliases,L21mt,MGC62013,MRP-L21,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.3
Gene position68671303 - 68658746  Map Viewer
Gene orientationminus
Gene size12558 bp
Gene sequence
OMIM ID611834