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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MARCH8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID220972
Official gene symbolMARCH8
Full namemembrane-associated ring finger (C3HC4) 8
Aliases,MARCH-VIII,MIR,RNF178,c-MIR,
Gene summaryMARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM]
LocationChromosome: 10   Locus: 10q11.21
Gene position46090354 - 45952817  Map Viewer
Gene orientationminus
Gene size137538 bp
Gene sequence
OMIM ID613335