Entrez gene ID | | 220972 |
Official gene symbol | | MARCH8 |
Full name | | membrane-associated ring finger (C3HC4) 8 |
Aliases | | ,MARCH-VIII,MIR,RNF178,c-MIR, |
Gene summary | | MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM] |
Location | | Chromosome: 10 Locus: 10q11.21 |
Gene position | | 46090354 - 45952817 Map Viewer |
Gene orientation | | minus |
Gene size | | 137538 bp |
Gene sequence |
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OMIM ID | | 613335 |