Entrez gene ID | | 2213 |
Official gene symbol | | FCGR2B |
Full name | | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
Aliases | | ,CD32,CD32B,FCG2,FCGR2,IGFR2, |
Gene summary | | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23 |
Gene position | | 161632905 - 161648444 Map Viewer |
Gene orientation | | plus |
Gene size | | 15540 bp |
Gene sequence |
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OMIM ID | | 604590 |