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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2243 Official gene symbol FGA Full name fibrinogen alpha chain Aliases ,Fib2,MGC119422,MGC119423,MGC119425, Gene summary The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq] Location Chromosome: 4   Locus: 4q28 Gene position 155511897 - 155504280  Map Viewer Gene orientation minus Gene size 7618 bp Gene sequence >FGA:complement(80052001..80059618):Length=7618 AGCAATCCTTTCTTTCAGCTGGAGTGCTCCTCAGGAGCCAGCCCCACCCTTAGAAAAGAT GTTTTCCATGAGGATCGTCTGCCTGGTCCTAAGTGTGGTGGGCACAGCATGGGTATGGCC CTTTTCATTTTTTCTTCTTGCTTTCTCTCTGGTGTTTATTCCACAAAGAGCCTGGAGGTC AGAGTCTACCTGCTCTATGTCCTGACACACTCTTAGCTTTATGACCCCAGGCCTGGGAGG AAATTTCCTGGGTGGGCTTGACACCTCAAGAATACAGGGTAATATGACACCAAGAGGAAG ATCTTAGATGGATGAGAGTGTACAAACTCACAAGGGAAACTTTAGCATCTGTCATTCAGT CTTACCACATTTTGTTTTGTTTTGTTTTAAAAAGGGCAAGAATTATTTGCCATCCTTGTA CCTATAAAGCCTTGGTGCATTATAATGCTAGTTAATGGAATAAAACATTTTATGGTAAGA TTTGTTTTCTTTAGTTATTAATTTCTTGCTACTTGTCCATAATAAGCAGAACTTTTAGTG TTAGTACAGTTTTGCTGAAAGGTTATTGTTGTGTTTGTCAAGACAGAAGAAAAAGCAAAC GAATTATCTTTGGAAATATCTTTGCAGTATCAGAAGAGATTAGTTAGTAAGGCAATACGC TTTTCCGCAGTAATGGTATTCTTTTAAATTATGAATCCATCTCTAAAGGTTACATAGAAA CTTGAAGGAGAGAGGAACATTCAGTTAAGATAGTCTAGGTTTTTCTACTGAAGCAGCAAT TACAGGAGAAAGAGCTCTACAGTAGTTTTCAACTTTCTGTCTGCAGTCATTAGTAAAAAT GAAAAGGTAAAATTTAACTGATTTTATAGATTCAAATAATTTTCCTTTTAGGATGGATTC TTTAAAACTCCTAATATTTATCAAATGCTTATTTAAGTGTCACACACAGTTAAGAAATTT GTACACCTTGTCTCCTTTAATTCTCATAACAACTCCATAAAATGGGTCCTAGGATTTCCA TTTGAAGATAAGAAACCTGAAGCTTGCCGAAGCCCTGTGTCTGCTCTCCTTAATCTCTGT GAGAGTGCCATCTCTTCCTGGGGACTTGTAGGCATGCCACTGTCTCCTCTTCTGGCTAAC ATTGCTGTTGCTCTCTTTTGTGTATGTGAATGAATCTTTAAAGACTGCAGATAGTGGTGA AGGTGACTTTCTAGCTGAAGGAGGAGGCGTGCGTGGCCCAAGGGTTGTGGAAAGACATCA ATCTGCCTGCAAAGATTCAGACTGGCCCTTCTGCTCTGATGAAGACTGGGTAAGCAGTCA GCGGGGGAAGCAGGAGATTCCTTCCCTCTGATGCTAGAGGGGCTCACAGGCTGACCTGAT TGGTCCCAGAAACTTTTTTAAATAGAAAATAATTGAATAGTTACCTACATAGCAAATAAA GAAAAGGAACCTACTCCCAAGAGCACTGTTTATTTACCTCCCCAACTCTGGATCATTAGT GGGTGAACAGACAGGATTTCAGTTGCATGCTCAGGCAAAACCAGGCTCCTGAGTATTGTG GCCTCAATTTCCTGGCACCTAATTTATGGCTAAGTGGACCCTCATTCCAGAGTTTCTCTG CGACCTCTAACTAGTCCTCTTACCTACTTTTAAGCCAACTTATCTGGAAGAGATAGGGTA GGAAGAAATGGGGGCTGCATGGAAACATGCAAAATTATTCTGAATCTGAGAGATAGATCC TTACTGTAATTTTCTCCCTTCACTTTCAGAACTACAAATGCCCTTCTGGCTGCAGGATGA AAGGGTTGATTGATGAAGTCAATCAAGATTTTACAAACAGAATAAATAAGCTCAAAAATT CACTATTTGAATATCAGAAGAACAATAAGGATTCTCATTCGTTGACCACTAATATAATGG AAATTTTGAGAGGCGATTTTTCCTCAGCCAATAGTAAGTATTACATATTTACTGCTTTGA CTTTATAACAGAAACAACAAAAATCCTAAATAAATATGATATCCGCTTATATCTATGACA ATTTCATCCCAAAGTACTTAGTGTAGAAACACATACCTTCATAATATCCCTGAAAATTTT AAGAGGGAGCTTTTGTTTTCGTTATTTTTTCAAAGTAAAAGATGTTAACTGAGATTGTTT AAGGTCACAAAATAAGTCAGAATTTTGGATTAAAAACAAGAATTTAAATGTGTTCTTTTC AACAGTATATACTGAAAGTAGGATGGGTCAGACTCTTTGAGTTGATATTTTTGTTTCTGC TTTGTAAAGGTGAAAACTGAGAGGTCAAGGAACTTGTTCAAAGACACAGAGCTGGGAATT CAACTCCCAGACTCCACTGAGCTGATTAGGTAGATTTTTAAATTTAAAATATAGGGTCAA GCTACGTCATTCTCACAGTCTACTCATTAGGGTTAGGAAACATTGCATTCACTCTGGGCA TGGACAGCGAGTCTAGGGAGTCCTCAGTTTCTCAAGTTTTGCTTTGCCTTTTTACACCTT CACAAACACTTGACATTTAAAATCAGTGATGCAACACTAGCTGGCAAGTGAGTGATCCTG TTGACCCAAAACAGCTTAGGAACCATTTCAAATCTATAGATTAAAAAGAAAAGCTCATCA GTAAGAAAATCCAATATGTTCAAGTCCCTTGATTAAGGATGTTATAAAATAATTGAAATG CAATCAAACCAACTATTTTAACTCCAAATTACACCTTTAAAATTCCAAAGAAAGTTCTTC TTCTATATTTCTTTGGGATTACTAATTGCTATTAGGACATCTTAACTGGCATTCATGGAA GGCTGCAGGGCATAACATTATCCAAAAGTCAAATGCCCCATAGGTTTTGAACTCACAGAT TAAACTGTAACCAAAATAAAATTAGGCATATTTACAAGCTAGTTTCTTTCTTTCTTTTTT CTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCT CCTTCCTTCCTTTCTTCCTTTCTTTTTTGCTGGCAATTACAGACAAATCACTCAGCAGCT ACTTCAATAACCATATTTTCGATTTCAGACCGTGATAATACCTACAACCGAGTGTCAGAG GATCTGAGAAGCAGAATTGAAGTCCTGAAGCGCAAAGTCATAGAAAAAGTACAGCATATC CAGCTTCTGCAGAAAAATGTTAGAGCTCAGTTGGTTGATATGAAACGACTGGAGGTAAGT ATGTGGCTGTGGTCCCAGATGTCCTTGTTTCTGAGTAGAGGGAAAAGGAAGGCGATAGTT ATGCACTGAGTGTCTACTATATGCAGAGAAAAGTGTTATATCCATCATCTACCTAAAAGT AGGTATTATTTTCCTCACTCCACAGTTGAAGAAAAAAAATTCAGAGATATTAAGTAAATT TTCCAACGGTACATAGATAGTAAATTTCAAAAGCAAATGTTCAGTCCCTGTCTAATTCCA AAGCCCATTACATCACCACACCTCTGAGCCCTCAGCCTGAGTTTCACCAAGGATCATTTA ATTAGCGTTTCCTTTGAGAGGGAATAGCACCTTACTCTTGATCCATTCTGAGGCTAAGAT GAATTAAACAGCATCCATTGCTTATCCTGGCTAGCCCTGCAATACCCAACATCTCTTCCA CTGAGGGTGCTCGATAGGCAGAAAACAGAGAATATTAAGTGGTAGGTCTCCGAGTCAAAA AAAATGAAACCAGTTTCCAGAAGGAAAATTAACTACCAGGAACTCAATAGACGTAGTTTA TGTATTTGTATCTACATTTTCTCTTTATTTTTCTCCCCTCTCTCTAGGTGGACATTGATA TTAAGATCCGATCTTGTCGAGGGTCATGCAGTAGGGCTTTAGCTCGTGAAGTAGATCTGA AGGACTATGAAGATCAGCAGAAGCAACTTGAACAGGTCATTGCCAAAGACTTACTTCCCT CTAGAGATAGGCAACACTTACCACTGATAAAAATGAAACCAGTTCCAGACTTGGTTCCCG GAAATTTTAAGAGCCAGCTTCAGAAGGTACCCCCAGAGTGGAAGGCATTAACAGACATGC CGCAGATGAGAATGGAGTTAGAGAGACCTGGTGGAAATGAGATTACTCGAGGAGGCTCCA CCTCTTATGGAACCGGATCAGAGACGGAAAGCCCCAGGAACCCTAGCAGTGCTGGAAGCT GGAACTCTGGGAGCTCTGGACCTGGAAGTACTGGAAACCGAAACCCTGGGAGCTCTGGGA CTGGAGGGACTGCAACCTGGAAACCTGGGAGCTCTGGACCTGGAAGTACTGGAAGCTGGA ACTCTGGGAGCTCTGGAACTGGAAGTACTGGAAACCAAAACCCTGGGAGCCCTAGACCTG GTAGTACCGGAACCTGGAATCCTGGCAGCTCTGAACGCGGAAGTGCTGGGCACTGGACCT CTGAGAGCTCTGTATCTGGTAGTACTGGACAATGGCACTCTGAATCTGGAAGTTTTAGGC CAGATAGCCCAGGCTCTGGGAACGCGAGGCCTAACAACCCAGACTGGGGCACATTTGAAG AGGTGTCAGGAAATGTAAGTCCAGGGACAAGGAGAGAGTACCACACAGAAAAACTGGTCA CTTCTAAAGGAGATAAAGAGCTCAGGACTGGTAAAGAGAAGGTCACCTCTGGTAGCACAA CCACCACGCGTCGTTCATGCTCTAAAACCGTTACTAAGACTGTTATTGGTCCTGATGGTC ACAAAGAAGTTACCAAAGAAGTGGTGACCTCCGAAGATGGTTCTGACTGTCCCGAGGCAA TGGATTTAGGCACATTGTCTGGCATAGGTACTCTGGATGGGTTCCGCCATAGGCACCCTG ATGAAGCTGCCTTCTTCGACACTGCCTCAACTGGAAAAACATTCCCAGGTTTCTTCTCAC CTATGTTAGGAGAGTTTGTCAGTGAGACTGAGTCTAGGGGCTCAGAATCTGGCATCTTCA CAAATACAAAGGAATCCAGTTCTCATCACCCTGGGATAGCTGAATTCCCTTCCCGTGGTA AATCTTCAAGTTACAGCAAACAATTTACTAGTAGCACGAGTTACAACAGAGGAGACTCCA CATTTGAAAGCAAGAGCTATAAAATGGCAGATGAGGCCGGAAGTGAAGCCGATCATGAAG GAACACATAGCACCAAGAGAGGCCATGCTAAATCTCGCCCTGTCAGAGGTATCCACACTT CTCCTTTGGGGAAGCCTTCCCTGTCCCCCTAGACTAAGTTAAATATTTCTGCACAGTGTT CCCATGGCCCCTTGCATTTCCTTCTTAACTCTCTGTTACACGTCATTGAAACTACACTTT TTTGGTCTGTTTTTGTGCTAGACTGTAAGTTCCTTGGGGGCAGGGCCTTTGTCTGTCTCA TCTCTGTATTCCCAAATGCCTAACAGTACAGAGCCATGACTCAATAAATACATGTTAAAT GGATGAATGAATTCCTCTGAAACTCTATTTGAGCTTATTTAGTCAAATTCTTTCACTATT CAAAGTGTGTGCTATTAGAATTGTCACCCAACTGATTAATCACATTTTTAGTATGTGTCT CAGTTGACATTTAGGTCAGGCTAAATACAAGTTGTGTTAGTATTAAGTGATGCTTAGCTA CCTGTACTGGTTACTTGCTATTAGTTTGTGCAAGTAAAATTCCAAATACATTTGAGGAAA ATCCCCTTTGCAATTTGTAGGTATAAATAACCGCTTATTTGCATAAGTTCTATCCCACTG TAAGTGCATCCTTTCCCTATGGAGGGAAGGAAAGGAGGAAGAAAGAAAGGAAGGGAAAGA AACAGTATTTGCCTTATTTAATCTGAGCCGTGCCTATCTTTGTAAAGTTAAATGAGAATA ACTTCTTCCAACCAGCTTAATTTTTTTTTTAGACTGTGATGATGTCCTCCAAACACATCC TTCAGGTACCCAAAGTGGCATTTTCAATATCAAGCTACCGGGATCCAGTAAGATTTTTTC TGTTTATTGCGATCAAGAGACCAGTTTGGGAGGATGGCTTTTGATCCAGCAAAGAATGGA TGGATCACTGAATTTTAACCGGACCTGGCAAGACTACAAGAGAGGTTTCGGCAGCCTGAA TGACGAGGGGGAAGGAGAATTCTGGCTAGGCAATGACTACCTCCACTTACTAACCCAAAG GGGCTCTGTTCTTAGGGTTGAATTAGAGGACTGGGCTGGGAATGAAGCTTATGCAGAATA TCACTTCCGGGTAGGCTCTGAGGCTGAAGGCTATGCCCTCCAAGTCTCCTCCTATGAAGG CACTGCGGGTGATGCTCTGATTGAGGGTTCCGTAGAGGAAGGGGCAGAGTACACCTCTCA CAACAACATGCAGTTCAGCACCTTTGACAGGGATGCAGACCAGTGGGAAGAGAACTGTGC AGAAGTCTATGGGGGAGGCTGGTGGTATAATAACTGCCAAGCAGCCAATCTCAATGGAAT CTACTACCCTGGGGGCTCCTATGACCCAAGGAATAACAGTCCTTATGAGATTGAGAATGG AGTGGTCTGGGTTTCCTTTAGAGGGGCAGATTATTCCCTCAGGGCTGTTCGCATGAAAAT TAGGCCCCTTGTGACCCAATAGGCTGAAGAAGTGGGAATGGGAGCACTCTGTCTTCTTTG CTAGAGAAGTGGAGAGAAAATACAAAAGGTAAAGCAGTTGAGATTCTCTACAACCTAAAA AATTCCTAGGTGCTATTTTCTTATCCTTTGTACTGTAGCTAAATGTACCTGAGACATATT AGTCTTTGAAAAATAAAGTTATGTAAGGTTTTTTTTATCTTTAAATAGCTCTGTGGGTTT TAACATTTTTATAAAGATATACCAAGGGCCATTCAGTACATCAGGAAAGTGGCAGACAGA AGCTTCTCTCTGCAACCTTGAAGACTATTGGTTTGAGAACTTCTCTTCCCATACCACCCA AAATCATAATGCCATTGGAAAGCAAAAAGTTGTTTTATCCATTTGATTTGAATTGTTTTA AGCCAATATTTTAAGGTAAAACTCACTGAATCTAACCATAGCTGACCTTTGTAGTAGAAT TTACAACTTATAATTACAATGCACAATTTATAATTACAATATGTATTTATGTCTTTTGCT ATGGAGCAAATCCAGGAAGGCAAGAGAAACATTCTTTCCTAAATATAAATGAAAATCTAT CCTTTAAACTCTTCCACTAGACGTTGTAATGCACACTTATTTTTTTCCCAAGGAGTAACC AATTTCTTTCTAAAACACATTTAAAATTTTAAAACTATTTATGAATATTAAAAAAAGACA TAATTCACACATTAATAAACAATCTCCCAAGTATTGATTTAACTTCATTTTTCTAATAAT CATAAACTATATTCTGTGACATGCTAATTATTATTAAATGTAAGTCGTTAGTTCGAAAGC CTCTCACTAAGTATGATCTATGCTATATTCAAAATTCAACCCATTTACTTTGGTCAATAT TTGATCTAAGTTGCATCTTTAATCCTGGTGGTCTTGCCTTCTGATTTTTAATTTGTATCC TTTTCTATTAAGATATATTTGTCATTTTCTCTTGAATATGTATTAAAATATCCCAAGC OMIM ID 134820