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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Wt1 (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID22431
Official gene symbolWt1
Full nameWilms tumor 1 homolog
AliasesD630046I19Rik,Wt-1
Gene summaryThis gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. This gene has also been reported to be imprinted, with preferential expression from the maternal allele. [provided by RefSeq]
LocationChromosome: 2   Locus: 2 E|2 58.0 cM
Gene position104966686 - 105013771  Map Viewer
Gene orientationplus
Gene size47086 bp
Gene sequence