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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGF4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2249
Official gene symbolFGF4
Full namefibroblast growth factor 4
Aliases,HBGF-4,HST,HST-1,HSTF1,K-FGF,KFGF,
Gene summaryThe protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.3
Gene position69590171 - 69587797  Map Viewer
Gene orientationminus
Gene size2375 bp
Gene sequence
OMIM ID164980