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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGF8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2253 Official gene symbol FGF8 Full name fibroblast growth factor 8 (androgen-induced) Aliases ,AIGF,HBGF-8,KAL6,MGC149376, Gene summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24 Gene position 103535759 - 103529887  Map Viewer Gene orientation minus Gene size 5873 bp Gene sequence >FGF8:complement(54334351..54340223):Length=5873 ACCCGCACCCTCTCCGCTCGCGCCCTGCTCAGCGCGTCCTCCCGCGGCGGCCCGCGGGAC GGCGTGACCCGCCGGGCTCTCGGTGCCCCGGGGCCGCGCGCCATGGGCAGCCCCCGCTCC GCGCTGAGCTGCCTGTGAGTACCGCGCCGCCCTGCCCCGCCACCCGCCCCCCGCGCCCCT CGCCTCACCCGCGCCTCTCTCTCCCGCCCGCTTTTGTCTCCCACAGGCTGTTGCACTTGC TGGTCCTCTGCCTCCAAGCCCAGGTGAGGAGGGGTGCGCGGAGGCGGGGGCCGGGCGCGC CGGTGTGAGACCCGGGTGGGCAGCGCCGGTCGGGGGCACCGGGACTGACTCTGCGGCCGG CGCGGGAGGGCTGAGGGCACCTTAGAAACCCAGCCCCGAGCCACCCCGAGGAGGGAGCTG AGGCACAGAGAGGTAGCACCCCTCCTGAGGTCACACAGCGAGTGAGTGGCCAGGATAGAA ACGAAGGTCTCGGAGCCCAGCACTGTCCCCCATGCATCCTCGCCGGCTGGGGGCATAGGG AACACCCAGCCGCCGAGGAAGGGGGCAGCCGCGGCCAGGGGATGGATGTTCGATGCCAGG GGAAGCCGGGTGACTGCAGCAGAGACCCTCTCAGCGCCCCTCGGGGGAGGCTTGTGGCCG ATTTGGCCCAATGATCGGGTGCCCAGGTTCCCTGCACTCTCAACATTTGCTCCGTAAATT TGTCTTTATAAATGTCAGGGGTCGGGGAGGGCTGCCTCCCTACTTAAAAGCGCCCTGCTC CTCTAGGAAGGCCCGGGCAGGGGCCCTGCGCTGGGCAGGGAGCTCGCTTCCCTGTTCCGG GCTGGCCGGGAGCCCCAGGGTGTCTCCCAACAGGTGGGTCCAGCTTCTCCCTGGGGCTCG TTCATCCTGGGCTGGGTCTGCCCGACTTGCGTGGGTGGGGGATGGTGGCCTGGGCTGGCA TGTTGGGGGAACCCCCAGCACCTGCTGGCGGCTTGGGGCAGTGAGGGGGACGCAGGGTGA TGGGGCCACTCGGGCCCCTGGGCGGAGTAGCATTATAATGGTGTATTGTGTATTTTTCAA TTTCCTAAAGGTAACTGTTCAGTCCTCACCTAATTTTACACAGCATGTGAGGGAGCAGAG CCTGGTGACGGATCAGCTCAGCCGCCGCCTCATCCGGACCTACCAACTCTACAGCCGCAC CAGCGGGAAGCACGTGCAGGTCCTGGCCAACAAGCGCATCAACGCCATGGCAGAGGACGG CGACCCCTTCGGTAAGGCGCGCTGAAGGTAGCTTGTGGGATGCGCGGCGCCTGGACCACC AGTCCCAACTGCACTGGCCGGGGGCCTGCAGGGTCCCCAGCTCAGAAGGGAAGGAGTTAA GGCAGAAAGGTGTCTTGAGGGTCAGCTGGGGAAGAGAGGGCTAGGGAAGGGGCCTCGGGG AGTACTTGGCCACAGGTGCCCCCTTCCCTGCCCAGCAAATGAATGAATCTAGGAATCTCC CTTTACACCTCCCCCCTTCATACACTCCTCCCCAGCTGCAGGTGGAGGCAGGGGGTTCAG GGGGAGGGGGCCTAGGTTTAAGGCAAGCGCTTGAAAGAGGATATGTCGCCAGGGCCCACA AAAGGAGAGTGGGAAAGAGAAGGGAGAGAAATCCCCTCAACTCTCCCAGTTGGAAAAGGA GGTTGCTGGGAACCCTTAAATACTTTAATCGGATGGGTCAATTTACACGTGGAAACTGGG CTTGGAAGGGGGCTCTCCCTGCTCCATTCCCTGGGGAACCCAGGCGGCTGGGGCAGGGCT CCCGGCTCCCTGTGGGGTGGCAAGTGCGGAGAGCTACTGCCGGCAGAGAGGCTGAGGACT GATTGATTTCTAAAACATTCAATATTCCTGCCTTGAAACGGGGCCAATTTCCAGAGTCCT GGATGTACCAAGAGAAAAGCAAGCCCTCTGGGCGGCTGGTGTTGTTTTTAGAGAGCGATT ATTGTGAGTTTAAAAACCTTTAAATAATGACCACGTTAAACAAGCATGAAAGGAGAGGGG AAGACTCTATTAAAATGTAATAAAAAGGTGAGGCATTTTAAGAGCTAAGAAGAAAAATGA AGAATGATATAAAACAGAAAAAGAACGAGCTTTTTTTCAGATGTGGAGTTTGAAAGGAGT TGCAAGTCTGTAAATGTTAAAAAAGAGGTTCAAGATTGTTCTCTCTGAATCTCTGGAGAG ACCCCTGCGTCTGGCAGAGCGATTAAAACTCTTCTTACTTTCACCTTTTTTAACATTTCC TGAATACTTTCTCCTCTTCTTGAGCCAGTTTGGGGGATCGAGTATGTCTCGCTGCATTTT TTCTGCATCGACGTAGCTGACTTCCCTTCAAAGCTGGAGGAGACATAATTTTCCTGGGAT AAATCTGTCACTGGGGTGGAAGAATAGGTTTGAAAATGTTAAGCTTTCCAAAAGCCCGGT CGGGAGAGCTGCCGTAAACTGCGGCCCCAGCTCCCCAGATCGGAGCAGATTCAACCGACA TGGGAGAGAGCGGGCTTTCTGGGGTGGGGGTGGGGGCGGCCTGCCTGGTGGCCGAGCTCC CCTACTGGGCTGGCAGAGCAGGCCTACCATCCCTTTGTCCCTCCAAATTAGCTGCTTGCT GCCCTTCTCAGCTTCTAAGGAGAGGAGACGAATGCCTGGCTCTTCCAGGGTTTGCTCTGT CAGAGCAAATGGCCCAGCATCCTTGGATTTCGGGGAGGGAAGCAGAAGTCAAGCTGGTGT GGGGGAATTCATCTTCAGACATCAGAGGAAGCCTGATGTCCACTTCTCTCCGTGGCCATA TAAGAGGTTTCCCGCCTTCCCTAGTCCCTGCCCCACAGCAGGATAGGAGCTGGAGGCCCT AAGAACAGAGGCTCAGGGTGTTCAGCCAGGACAGGAGTAGTCCGGGGAGAATAGCAGAGA GGTCTCAATGGCTTCTTTACCGGCCCCAGGAAGATGCAGAGGCACCTACTTCATCCCTGC CTGCCGCATCTGGCCAGAATCCCCAGAGTGGCATCCTCTCACTCCTCCAGTCAGCATCCT TCCTGGCCCTTAAAAATAGCTGCCTCTTGCTGTGGAAGGCAGAGCGGGAGAGGGATGAGC AGACTGGCTAGGTCCAGGAGGAGGTGGGCAGGCAGGGAGGTGACAGCTGCATTTCCCTGC TGACTTGGGGCCAAACCGGGGGCTTGGCCACTGGTCCCAGCACTGAGCCTGTGTGAAGCG GGGAACATTACAAGCTGAGCAGTGATGACTGACTTGCTGACCTCGATGCCCCAAACCCCT GCCATGGGTTTCAGGGACAGAGGAGGTGCCATATGTCAATGCAGGCTAAGTCCAAGAACT GCTTTCTCAGGGAGGGGAGAGGCTGGGCTCTGCGGCAGGGACGGCAGGAGAGCCAGCGCC TTCTGTCCCTTCCTAAACAGTGAAGTCACCCTCACTACTTTCTTGAGGACAGCCTATAAG AGATGATTGCACAGAGAGGTGAACAGGACAGGCTTCTGTGGCAAGTTGGCTGTCTAAGGG GAGGGGAATGGGAAAGGAGGCATAGAATTCAGCCCTGCCTCCTGGCCTCCAGTCTAAGAG GCCAGCAGGCAGGATTCTCCCTCCTCCTCACCCACAGAAGCTATTTGGTCACTGGGCTGA GAAGCCCAGCTGTGATGAGGCTGAAAGAGAAAAGACAATTGAGTTGTTGATTTCTAGACA CTGGGCTGGGGACCCTGGTGACTGGGAAGCCACAGGGAAGAGGCAGGATCCTCCTGGCAG GTGTCTGAGGTTCTGGGAAAGCAGCCTGCTTTGGGCTGTGTGTTTAGGGAGAGCTGTCCC CATCCCTAGCACCTTCTCAGCAGAGCAGAGCCTGGTGATGTTGAGGGGCTGGGGGTGGCC AAAGCTGTGAGTTAGAACCCAAAGTGGCAGAAACAGGAGACAATGCTTTCATCTTTGGCC TTGGGACTGGAGGTCACCCCTTCACCCAAGTGTTTGTAATGACCTGTGAGACACGCACAC ATAATATTTGGAGTTGGAAGGATCCTCGGAGATCTTTTGATTAGCTATGGAACTCTGATT CAATTAAATTTTACTTAGATCCTCAATCTAAGAGACATCACTGTCTGGTTTAAAAAGAGG GTGGAAGGAATGGCACTTCAGCCTTTTCAATTTGATAGTCCCAAGACCTCTCTTGAGAAC CCAGTTTGAAAACCATAATCCCGTCCACTGCCCTCTGTAAACCCAGGGGTGGGGCCCGAG GTCCAGAAAAGCCCTTTCTCTGGGTTGCACAGCATGTTAGTAGCTGGGCTGGAGCTGGAG TCCATGTTTTGGGTTCCTGGTCTTTGGAGCAGTTGCTGCTGGGCTGTGACAAGTGTGTGG GCCAGCTGGGGTCAGGGATCTGCCAATAGCCATCCTGCTACCTTCTCTGACAGCAAAGCT CATCGTGGAGACGGACACCTTTGGAAGCAGAGTTCGAGTCCGAGGAGCCGAGACGGGCCT CTACATCTGCATGAACAAGAAGGGGAAGCTGATCGCCAAGGTGAGGCCCCAGCAGGCAGG TGGGGTCCGCGGGACCTAGGGAGTGGCTTGGGCTGGCTGGACTCCTCCAAGACAGTCCTG GGCTCTGATCCCAACAAGGTAGGCAGAAGGCCACAGGGCCATCTTGGGGTTACCTCACGA TTGGGTGCAGGAGTGAGGGAGAAGGAAGCTGTTTGAGAGATGAAAACTATAAAAGGCGAA GGAGGAAGAATGAAGGCTAGGGAAGGGGCTGGGGGGTGGTGGTTGGTAAATTCCATATAT CTTTTTAACAAATCGCCAAATTGCTTTGCTATTATGTCCAATTACATGGTACCAGCATTT GGAATGTTCAGTAAGCCGCAGGCCCAGCCCCTCGGCCGAGCTCTGAAATGGCTCCATTAG TCACGGCTCCTCTCCAGCCTCGAGCTCCCCACTTCCTGGGCTTCTGGGGCTGGGGTCTTA GCATCTTCTCCCAGGCCTCCCCTCCCCCATAGGGTGGCTGCCCTGGGGCCAGGGAACCGA AGTCCTGGGGGGGTGAGAGGGGCAGGTGGGGAGACGGGTGGCCAGACTGGTGGGCAGGAG GCCAGAGCAGGCCAGGCTCTGGGCCCCTCTCTCTGTCTTTCTGCGTTGGGGCCCAGCCCC TCCGTAGACAACCATGTGTCACTGCTGCCTGGGAGGACAGGAAGTTGCCGGGTGGGCTGC GAGTTGTGAGGGATTAGAGAGCGGGTGCCCAGGCAGGGGGTGGGGCTGCGGCTCCTGCCC ACCTCGCCATCTGCTGGGGTGCCCACCTGCTGTCTGGGGCCGCTCGCCCTCTGCCTCTGC TGGGGGGGCTCTGTAACGTGGTGTCTGGCTCCCCTACCTGCAGAGCAACGGCAAAGGCAA GGACTGCGTCTTCACGGAGATTGTGCTGGAGAACAACTACACAGCGCTGCAGAATGCCAA GTACGAGGGCTGGTACATGGCCTTCACCCGCAAGGGCCGGCCCCGCAAGGGCTCCAAGAC GCGGCAGCACCAGCGTGAGGTCCACTTCATGAAGCGGCTGCCCCGGGGCCACCACACCAC CGAGCAGAGCCTGCGCTTCGAGTTCCTCAACTACCCGCCCTTCACGCGCAGCCTGCGCGG CAGCCAGAGGACTTGGGCCCCCGAGCCCCGATAGGTGCTGCCTGGCCCTCCCCACAATGC CAGACCGCAGAGAGGCTCATCCTGTAGGGCACCCAAAACTCAAGCAAGATGAGCTGTGCG CTGCTCTGCAGGCTGGGGAGGTGCTGGGGGAGCCCTGGGTTCCGGTTGTTGATATTGTTT GCTGTTGGGTTTTTGCTGTTTTTTTTTTTTTTTTTTTTTTTAAAACAAAAGAG OMIM ID 600483