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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2268
Official gene symbolFGR
Full nameGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
Aliases,FLJ43153,MGC75096,SRC2,c-fgr,c-src2,p55-Fgr,p55c-fgr,p58c-fgr,
Gene summaryThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.2-p36.1
Gene position27961727 - 27938800  Map Viewer
Gene orientationminus
Gene size22928 bp
Gene sequence
OMIM ID164940