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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IKZF3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID22806
Official gene symbolIKZF3
Full nameIKAROS family zinc finger 3 (Aiolos)
Aliases,AIO,AIOLOS,ZNFN1A3,
Gene summaryThis gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21
Gene position38020441 - 37921198  Map Viewer
Gene orientationminus
Gene size99244 bp
Gene sequence
OMIM ID606221