Entrez gene ID | | 2281 |
Official gene symbol | | FKBP1B |
Full name | | FK506 binding protein 1B, 12.6 kDa |
Aliases | | ,FKBP12.6,FKBP1L,OTK4,PKBP1L,PPIase, |
Gene summary | | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p23.3 |
Gene position | | 24272584 - 24286551 Map Viewer |
Gene orientation | | plus |
Gene size | | 13968 bp |
Gene sequence |
| |
OMIM ID | | 600620 |