Entrez gene ID | | 2286 |
Official gene symbol | | FKBP2 |
Full name | | FK506 binding protein 2, 13kDa |
Aliases | | ,FKBP-13,PPIase, |
Gene summary | | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13.1-q13.3 |
Gene position | | 64008413 - 64011607 Map Viewer |
Gene orientation | | plus |
Gene size | | 3195 bp |
Gene sequence |
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OMIM ID | | 186946 |
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