Entrez gene ID | | 22919 |
Official gene symbol | | MAPRE1 |
Full name | | microtubule-associated protein, RP/EB family, member 1 |
Aliases | | ,EB1,MGC117374,MGC129946, |
Gene summary | | The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q11.1-q11.23 |
Gene position | | 31407699 - 31438211 Map Viewer |
Gene orientation | | plus |
Gene size | | 30513 bp |
Gene sequence |
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OMIM ID | | 603108 |
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