Entrez gene ID | | 22928 |
Official gene symbol | | SEPHS2 |
Full name | | selenophosphate synthetase 2 |
Aliases | | ,SPS2, |
Gene summary | | This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p11.2 |
Gene position | | 30457224 - 30454952 Map Viewer |
Gene orientation | | minus |
Gene size | | 2273 bp |
Gene sequence |
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OMIM ID | | 606218 |
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