Entrez gene ID | | 22933 |
Official gene symbol | | SIRT2 |
Full name | | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) |
Aliases | | ,SIR2,SIR2L,SIR2L2, |
Gene summary | | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13 |
Gene position | | 39390502 - 39369195 Map Viewer |
Gene orientation | | minus |
Gene size | | 21308 bp |
Gene sequence |
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OMIM ID | | 604480 |
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