| Entrez gene ID | | 22938 |
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| Official gene symbol | | SNW1 |
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| Full name | | SNW domain containing 1 |
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| Aliases | | ,Bx42,MGC119379,NCOA-62,PRPF45,Prp45,SKIIP,SKIP, |
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| Gene summary | | This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq] |
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| Location | | Chromosome: 14 Locus: 14q24.3 |
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| Gene position | | 78227497 - 78183942 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 43556 bp |
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| Gene sequence |
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| OMIM ID | | 603055 |
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